Registration Dossier
Registration Dossier
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EC number: 210-954-1 | CAS number: 626-58-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction
Data source
Reference
- Reference Type:
- other: (Q)SAR
- Title:
- Estimation Programs Interface Suite™ for Microsoft® Windows, v 4.11 (EPIWEB 4.11)
- Author:
- United States Environmental Protection Agency, Washington, DC, USA.
- Year:
- 2 012
- Bibliographic source:
- ECOSAR (v1.11) Program
Materials and methods
Test guideline
- Guideline:
- other: REACH Guidance on (Q)SAR
- Principles of method if other than guideline:
- (Q)SAR
Test material
- Reference substance name:
- 4-methylpiperidine
- EC Number:
- 210-954-1
- EC Name:
- 4-methylpiperidine
- Cas Number:
- 626-58-4
- Molecular formula:
- C6H13N
- IUPAC Name:
- 4-methylpiperidine
- Test material form:
- liquid
Constituent 1
Test organisms
- Test organisms (species):
- other: Green algae
Study design
- Test type:
- other: (Q)SAR
- Water media type:
- freshwater
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 3.557 mg/L
- Dose descriptor:
- other: Chronic Value (ChV)
- Effect conc.:
- 1.143 mg/L
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- Aliphatic Amines: Maximum LogKow: 7.0 (Green Algae EC50) - 7.0 (Chronic Value)
- Conclusions:
- Estimated EC50 (96h) : 3.5 mg/L
Estimated Chronic Value : 1.1 mg/L
Intermediate substance is not estimated to be toxic to aquatic algae.
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