Registration Dossier
Registration Dossier
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EC number: 607-713-1 | CAS number: 253768-88-6
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- January 2005
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Materials and methods
- GLP compliance:
- no
Test material
- Reference substance name:
- : (-)-trans-4-(4-fluorophenyl)-3-(3,4-methylendioxiphenoxymethyl)-1-phenoxycarboxy-piperidine
- EC Number:
- 607-713-1
- Cas Number:
- 253768-88-6
- Molecular formula:
- C26H24NO5F
- IUPAC Name:
- : (-)-trans-4-(4-fluorophenyl)-3-(3,4-methylendioxiphenoxymethyl)-1-phenoxycarboxy-piperidine
Constituent 1
In vitro test system
- Test system:
- other:
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Observation period:
- 3 days
- Number of animals:
- 3
Results and discussion
In vivo
- Irritant / corrosive response data:
- The product analysed does not cause any edema nor erythema which could be detected after 4 hours of contact of the sample within the test experimentation conditions
Applicant's summary and conclusion
- Interpretation of results:
- other: Not classified
- Conclusions:
- Non corrosive and non irritant product by skin contact
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