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EC number: 220-293-0 | CAS number: 2706-28-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Justification for type of information:
- Data is from GSBL
- Qualifier:
- according to guideline
- Guideline:
- other: refer below principle
- Principles of method if other than guideline:
- Short term toxicity was studied in Pseudomonas fluorescens by BringmannKühnTest.
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Pseudomonas fluorescens
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 24 h
- Reference substance (positive control):
- not specified
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- 5 000 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- other: Mortality
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- 5 000 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- other: swimming behavior
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- 5 000 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- other: Cell proliferation inhibition
- Validity criteria fulfilled:
- not specified
- Conclusions:
- In toxicity to micro organism the effective concentration i.e EC0 value for test substance Disodium 2-amino-5-[(4-sulphonatophenyl)azo]benzenesulphonate (2706-28-7) was found to be 5000 mg/l on Pseudomonas fluorescens by the method BringmannKühnTest for 24 hrs.
- Executive summary:
In Toxicity to microorganism study conducted according to Bringmann Kühn Test method on test species Pseudomonas fluorescens for 24 hrs.
During experiment the effective concentration i.e EC0 was found to be 5000 mg/l on the basis of mortality,swimming behavior and Cell proliferation inhibition effects.
Thus based on above mentioned effective concentration the test substance Disodium 2-amino-5-[(4-sulphonatophenyl)azo]benzenesulphonate (2706-28-7) consider to be non toxic to micro organisms.
Reference
Description of key information
In toxicity to micro organism the effective concentration i.e EC0 value for test substance Disodium 2-amino-5-[(4-sulphonatophenyl)azo]benzenesulphonate (2706-28-7) was found to be 5000 mg/l on Pseudomonas fluorescens by the method BringmannKühnTest for 24 hrs.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 5 000 mg/L
Additional information
Toxicity to micro organism was assessed for the target compound Disodium 2-amino-5-[(4-sulphonatophenyl)azo]benzene sulphonate (2706-28-7) and its related read- across. The summary of the results are presented below:
In Toxicity to microorganism study for test substance Disodium 2-amino-5-[(4-sulphonatophenyl)azo]benzene sulphonate conducted according to Bringmann Kühn Test method on test species Pseudomonas fluorescens for 24 hrs.
During experiment the effective concentration i.e EC0 was found to be 5000 mg/l on the basis of mortality, swimming behaviour and Cell proliferation inhibition effects.
Whereas experimental study (Chemophere. Vol. 28, No. 12, pp. 2203.2236, 1994) for read across substance 2,2'-(1,2-Ethenediyl)bis(5-aminobenzenesulfonic acid) disodium salt (Cas no. 7336-20-1)indicate that the effect concentrations i.e EC0 of test substance for bacteria (unadapted biological waste water treatment plant) was found to be 1000 mg/l for 24 hrs.
And other experimental study report from HPVIS database for same read across substance i.e 2,2'-(1,2-Ethenediyl)bis(5-aminobenzenesulfonic acid) disodium salt (Cas no. 7336-20-1) indicate that the EC0 was found to be >300 mg/l and EC50 is >100 mg/l for 3 hrs.on Bacteria (activated sludge) and on the basis of growth inhibition effect. For 24 hrs on Pseudomonas fluorescens species effect concentration (EC0)was resulted as 1000 mg/l and Photobacterium phosphoreum species for 45 min study the EC50 was found to be >500 mg/l.
Based on above available studies it is concluded that the substance Disodium 2-amino-5-[(4-sulphonatophenyl)azo]benzene sulphonate (2706-28-7)was consider to be non toxic to micro organisms.
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