Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 226-133-6 | CAS number: 5292-43-3
Endpoint summary
Administrative data
Description of key information
Not skin sensitizer.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
The Guinea Pig Maximisation Test was performed according to OECD 406 (1992). A total of 27 animals were used, 15 for the main study (10 test and 5 control) and 12 for the primary study.
The induction phase was accomplished by both intradermal and epicutaneous application. In the challenge phase, the test substance resulted in a sensitisation rate of 0 %, when tested at the maximum testable epidermal applications of 0.5 and 1 % v/v test article.
Conclusion
The substance did not show sensitising effects on tested animals.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
According to the Regulation EC 1278/2008 (CLP) the substance does not meet the criteria for classification, since the sensitisation rate is lower than 30 %, minimum threshold value required for classification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
