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Diss Factsheets
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EC number: 209-424-2 | CAS number: 578-54-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
2-ethylaniline is not classified as a skin irritant but it is probably eye irritant.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
As reported in Chemical Information Profile for Alkylaniline NTP 2009 with reference to U.S. EPA (Environmental Protection Agency). 2006. High Production Volume (HPV) Challenge Program. Robust Summaries & Test Plans: Ring Substituted Anilines Category. Cover letter (dated May 4, 2006), test plan, and robust summaries submitted to the U.S. EPA Chemical Right-to-Know Program by Dr. Len Sweet of Albemarle Corporation, Baton Rouge, LA, pp.121 2-ethylaniline was not classified as a skin irritant in rabbits but was a mild eye irritant. No details regarding these studies are reported in Chemical Information Profile for Alkylaniline NTP 2009.
In this summary are reported data owner studies published by NTP. They have been used for precautionary purposes and for the benefit of the human health .Those data are not necessary for the registration of the target substance which is used exclusively as isolated and transported intermediate, but they can be very helpful for a better definition of the toxicological property of the substance. No other use and no commercial advantage will derive from the use of those data.
Based on precautionary principle and according to the CLP Regulation (EC n. 1272/2008) the classification H319 (Eye Irrit. cat.2) is proposed for 2-ethylaniline.
Justification for classification or non-classification
As reported in Chemical Information Profile for Alkylaniline NTP 2009 2-ethylaniline was not classified as a skin irritant in rabbits but was a mild eye irritant.
Based on precautionary principle and according to the CLP Regulation (EC n. 1272/2008) the classification H319 (Eye Irrit. cat.2) is proposed for 2-ethylaniline.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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