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EC number: 262-038-6 | CAS number: 60047-17-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP compliant study conducted according to OECD Guidelines, with no or minor deviations.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-(tetrahydro-5-methyl-5-vinyl-2-furyl)propan-2-ol
- EC Number:
- 262-038-6
- EC Name:
- 2-(tetrahydro-5-methyl-5-vinyl-2-furyl)propan-2-ol
- Cas Number:
- 60047-17-8
- Molecular formula:
- C10H18O2
- IUPAC Name:
- 2-(5-methyl-5-vinyltetrahydrofuran-2-yl)propan-2-ol
- Test material form:
- other: liquid
- Details on test material:
- Name: Linalool Oxide
Batch No.: PE00097239
Purity: 98.5 % (Sum of cis- and trans- isomers)
Expiry date: 2016-08-27
Please note that although the substance is described in the report with the IUPAC name: 2-(5-methyl-5-vinyltetrahydrofuran-2-yl)propan-2-ol related to the CAS number 1365-19-1, recent analytical data had been determined the substance to be a multi-constituent 2-(tetrahydro-5-methyl-5-vinyl-2-furyl)propan-2-ol related to the CAS number 60047-17-8..
As the chemical manufacturing process has not changed since the report was written, the recent analytical information is relevant to the batch which was tested.
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- Exposure concentrations were monitored at the start (0 and 24h) and at the end (24 and 48h) of each renewal period.
Test solutions
- Vehicle:
- no
- Details on test solutions:
- A limit concentration of the test item of 125 mg/L was tested, which corresponds to a geometric mean measured test item concentration of 117 mg/L.
The limit concentration was selected based on the results of a non-GLP preliminary range finding test in order to achieve a mean measured test item concentration of at least 100mg/L. In this range-finder test no effects were observed in any of the tested concentration levels.
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Daphnia magna STRAUS (Clone 5)
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Remarks on exposure duration:
- Immobilisation was determined in all groups after 24 and 48 h.
Test conditions
- Nominal and measured concentrations:
- Non-GLP range-finder: 100mg/L (nominal) with corresponding measured concentrations ranging from 70.5 to 96.2mg/L; and 10 mg/L (nominal) with correpsonding measured concentrations ranging from 7.05 to 9.99 mg/L.
Definitive Limit Test: 125mg/L (nominal), 117 mg/L (geometric mean measured concentration)
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 117 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC10
- Effect conc.:
- > 117 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- > 117 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- At the limit nominal concentration of 125 mg/L of the test item Linalool Oxide, which corresponds to a geometric mean measured test item concentration of 117 mg/L, no effects were observed on Daphnia magna.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- No effects were observed on Daphnia magna in a limit test performed at a nominal concentration of 125 mg/L of the test item Linalool Oxide, which corresponds to a geometric mean measured test item concentration of 117 mg. Thus the EC50 was determined to be > 117 mg/L.
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