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EC number: 939-125-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48 h) = 331 mg/L nominal, Daphnia magna (DIN 38412 Part 1; EG Guideline 92/69/EWG), read across
Key value for chemical safety assessment
Additional information
There are no data available on the acute toxicity to aquatic invertebrates of “hydrolysis product of 3-(triethoxysilyl)propan-1-amine > 0.1% - <16%
” (EC no. 939-125-9). In order to fulfil the standard information requirements set out in Annex VIII, read-across from a structurally related substance ( 3-(triethoxysilyl)propan-1-amine, CAS no. 919-30-2), is conducted in accordance with Annex XI, 1.5, of Regulation (EC) No 1907/2006.This read-across is based on the hypothesis that the starting material, 3-(triethoxysilyl)propan-1-amine, hydrolyses rapidly in water resulting in the target substance. It can be expected that both the target and the source substance have similar behaviour under the aqueous conditions. The target substance consists of the hydrolysis product 3-aminopropylsilanetriol and condensation products dimers, trimers and polymers of siloxanes which have similar functional groups (-O-Si- or HO-Si-). Therefore, it is considered that the target substance and 3-aminopropyltriethoxysilane are in one class of compounds and structural differences are not supposed to contribute to significant differences in activity with respect to eco- and human toxicological endpoints. The other hydrolysis product is ethanol, which is well described in the public domain to have no adverse environmental effects.
A detailed analogue approach justification is provided in the technical dossier (Please refer to IUCLID Section 13 for further information).
The acute toxicity of 3-(triethoxysilyl)propan-1-amine (CAS no. 919-30-2) to aquatic invertebrate species has been investigated in a study by Evonik (1993). This test was performed according to DIN 38412 Part 1; EG Guideline 92/69/EWG under GLP conditions. Daphnia magna was exposed to the test substance for 48 hours within a static water regime at the following nominal test substance concentrations: 0, 8.7, 16.4, 28.4, 54.7, 94.0, 174.9, 306.0, 546.5, and 983.7 mg/L. Nominal test substance concentrations were established based on DOC measurement of the stock solution. No further analytical dose verifications were performed. Effects were monitored every 24 hours until the end of the experiment. An EC50 (48 h) of 331 mg/L (nominal) was determined.
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