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EC number: 242-828-7 | CAS number: 19125-99-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16-09-2016 – 22-09-2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Experimental test result performed using standard test guidelines
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- flask method
- Key result
- Water solubility:
- 0.051 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 28 °C
- Remarks on result:
- other: othr detals not spcecified
- Conclusions:
- The water solubilitydetermination of test item 2-butyl-6-(butylamino)-1H-benz[de]isoquinoline-1,3(2H)-dione;CAS No.19125-99-6 was done by spectrophotometric method. The water solubility was found to be 0.0507 mg/L at 28°C.
- Executive summary:
The water solubility determination of test item 2-butyl-6-(butylamino)-1H-benz[de]isoquinoline-1,3(2H)-dione (CAS No. 19125 -99-6) was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of (2-butyl-6-(butylamino)-1H-benz[de]isoquinoline-1,3(2H)-dione of 19125-99-6 )in water was found to be 0.0507 mg/L at 28°C. This indicates the test substance to be insoluble in water.
Reference
Table 1:
Sr. No. |
Aliquot of stock solution taken (ml) |
Amount of water added to make up the volume (ml) |
Concentration of Standard Solution (mg/l) |
1. |
4 |
16 |
4 |
2. |
8 |
12 |
8 |
3. |
12 |
8 |
12 |
4. |
16 |
4 |
16 |
5. |
20 |
0 |
20 |
The absorbances of these standard solutions were taken at446 nm (λ max) and the standard curve was plotted between absorbance versus concentrations (mg/l). The spectrophotometer used for the analysis was UV-6300PC; make VWR.
Description of key information
The water solubilitydetermination of test item 2-butyl-6-(butylamino)-1H-benz[de]isoquinoline-1,3(2H)-dione;CAS No.19125-99-6 was done by spectrophotometric method. The water solubility was found to be 0.0507 mg/L at 28-°C.
Key value for chemical safety assessment
- Water solubility:
- 0.051 mg/L
- at the temperature of:
- 28 °C
Additional information
The water solubility determination of test item 2-butyl-6-(butylamino)-1H-benz[de]isoquinoline-1,3(2H)-dione (CAS No. 19125 -99-6) was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of (2-butyl-6-(butylamino)-1H-benz[de]isoquinoline-1,3(2H)-dione of 19125-99-6 )in water was found to be 0.0507 mg/L at 28 °C.
Other supporting data from EPI suite modeling database estimates the solubility as 0.14 mg/L, which also indicates the marginal solubility or negligibly solubility in water.
Thus the test substance 2-butyl-6-(butylamino)-1H-benz[de]isoquinoline-1,3(2H)-dione is concluded to be insoluble in water considering 0.0507 mg/L as the key value for safety assessment.
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