Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

The toxicity for soil organisms (plants and microorganisms) of n-butyl phosphorothioc triamide (nBPT), the main contituent of the reaction mass, was assessed on the basis of studies conducted with urea fertilizer containing the urease inhibitor. These studies, performed at concentrations reflecting application rates of fertlizers normally adopted in agriculture, have showed a very low toxicity of the urease inhibitor towards soil organisms.

The PNEC(soil) has been calculated using an assessment factor instead of applying the equilibrium partition method because several studies have been conducted that cover the short-term terrestrial toxicity (data for two trophic levels available: terrestrial plants and soil microorganisms). This leads to a more realistic risk assessment for the terrestrial compartment than relying on aquatic toxicity data. The most sensitive effect concentration stems from toxicity-testing with soil microorganisms resulting in an EC50 of 0.05 mg/kg dw soil (Bremner et al., 1986) which was used for calculation of the PNEC(soil) in combination with an assessment factor of 1000.