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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

OECD 218, GLP [[i]]
Chironomus riparius, 28 days, static, freshwater
EC50 = 22.35 µg/kg dry weight and NOEC = 10.15 µg/kg d.w., based on emergence ratio.
EC50 > 44.43 µg/kg d.w. and NOEC = 25.16 µg/kg d.w., based on development rate.


[i]         Hargreaves, T. L., & Green, M. A. (2007). The Effects of [3H]-Doramectin Spiked into Sediment on the Sediment-Dwelling Larvae of the Freshwater Midge Chironomus Riparius Meigen (Diptera: Chironomidae). Charles River Laboratories, UK, study 806913, report 27663 (Pfizer study 1A73N-03-06-375).
ZRD-STU-017520