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EC number: 292-771-7 | CAS number: 90990-10-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The aquatic toxicity of fatty acids has been evaluated in studies on fish, daphnids and algae as well as microorganisms. Most of the studies were conducted with fatty acid homologues. Most tests are available for the soluble fatty acids octanoic acid C8 (CAS 124 -078 -2), azelaic acid C9 (CAS 123 -99 -9), decanoic acid C10 (CAS 334 -48 -5) and lauric acid C12 (CAS 143 -07 -7). In addition some studies were conducted with the insoluble pure homologues myristic acid C14 (CAS 544 -63 -8), palmitic acid C16 (CAS 57 -10 -3) and stearic acid C18 (CAS 57 -11 -4) and certain mixtures of the fatty acid category.
Regarding the composition of the C12 -14 fatty acid mixture (CAS 90990 -10 -6), the main components (fatty acid homologues with a content >10%) are:
- C12: 65 - 85% C12
- C14: 15 - 35% C14
The evaluation of the risk of the considered fatty acid mixture to aquatic organisms was predominantly based on studies available for the main components. A detailed justification for the grouping of chemicals and read-across is provided in the Category Justification (see section 13 of the technical dossier).
Regarding the acute toxicity of fatty acids to aquatic organisms, lauric acid (C12: CAS 143-07-7) was found as the most toxic component of the mixture C12 - C14 fatty acids (CAS 90990 -10 -6), as it is the most soluble homologue contained in the mixture. Regarding the acute toxicity, aquatic invertebrates are most sensitive to lauric acid, followed by fish. For algae no effects up to the limit of water solubility was observed.
Chronic fish toxicity data with lauric acid are not available. Therefore data from a surrogate substance, sodium laurate (CAS 629-25-4, C12) were taken into account. From this test it was concluded, that long-term effects on fish up to the limit of water solubility are not expected for the mixture C12 - C14 fatty acids (CAS 90990 -10 -6). The chronic toxicity on aquatic invertebrates was assessed based on a study conducted with decanoic acid (CAS 334-48-5). This study was performed within (an ongoing) test program in cooperation with the Fraunhofer Institute IME (FhG) in Schmallenberg/Germany. In the test no immobilisation occurred throughout the test, neither the mean cumulative offspring was affected by the test substance. A NOELR of >= 1.3 mg/L (measured, TWA) was determined, which corresponds to a nominal loading of 5 mg/L. An additional study on chronic invertebrate toxicity of lauric acid, which was designed to overcome methodological deficiencies and revise the environmental hazard, is still ongoing.
Within the fatty acids category, studies describing the toxicity of these substances on Pseudomonas putida are available. For the mixture C12 - C14 fatty acids (CAS 90990 -10 -6) read across data from five studies on C8, C12 and C14 chain lengths were used. All read across data showed that no toxicity of the substance to microorganisms is expected.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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