2-[(2-[2-(dimethylamino)ethoxy]ethyl)methylamino]ethanol

Density

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

density, other

Remarks:

average density

Type of information:

experimental study

Adequacy of study:

weight of evidence

Study period:

2003-02-26 to 2003-06-05

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

GLP compliance:

yes (incl. QA statement)

Remarks:

Report represents data generated in the “spirit of” Good Laboratory Practice. GLP deviations were that a Study Plan was not written, however Study-Specific Supplements were provided to study personnel describing laboratory work in detail.

Type of method:

other: weight determination of know volume of test substance

Specific details on test material used for the study:

- Name of test material (as cited in study report): Jeffcat ZF-10, 2-((2-(2-(dimethylamino)ethoxy)ethyl)methyl-amino)-ethanol
- Substance type: Amine
- Physical State: Clear colourless liquid
- Analytical purity: 99%
- Lot/batch No.: 324756
- Storage condition of test material: 22 °C in the dark

Key result

Type:

density

Density:

0.94 other: g/ml

Temp.:

23.5 °C

Conclusions:

The observed average density of the test substance was 0.9428 ± 0.0003 g/mL at 23.5°C.

Reference 2

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

weight of evidence

Study period:

1990-05-14 to 1990-07-03

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Study conducted according to the pycnometer method as described in ISO Recommendation R1183, in accordance with EEC Directive 67/548, Annex V, A3, as published in 84/449/EEC. Study follows GLP. Study methods similar to OECD guidelines.

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

GLP compliance:

yes (incl. QA statement)

Type of method:

pycnometer method

Specific details on test material used for the study:

- Name of test material (as cited in study report): Texacat ZF-10, 2-[[2-[2-(dimethylamino)ethoxy]ethyl]methylamino]ethanol
- Physical state: Clear colorless liquid
- Analytical purity: 97%
- Lot/batch No.: 90/329
- Expiration date of the lot/batch: Approximately

Type:

density

Density:

954.4 kg/m³

Temp.:

20 °C

Key result

Type:

relative density

Density:

0.954

Temp.:

20 °C

Conclusions:

The relative density of the test substance has been determined to be 0.9544 at 20°C.

Description of key information

The relative density of the test substance was determined to be 0.95 at 20°C based on two studies in a weight of evidence approach.

A density of 0.9428 ± 0.0003 g/mL at 23.5°C was determined according to the OECD guideline 109 by BC Research Inc. (2003). GLP deviations were that a study plan was not written, however study-specific supplements were provided to study personnel describing laboratory work in detail. The study was considered to be reliable without restrictions (Klimisch 1).

A second study performed according to the pycnometer method as described in ISO Recommendation R1183, in accordance with EEC Directive 67/548, Annex V, A3, as published in 84/449/EEC, by Huntingdon Research Centre Ltd. (1990) and considered reliable without restrictions (Klimisch 1) reports a relative density of 0.9544 at 20°C.

Key value for chemical safety assessment

Relative density at 20C:

0.95