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EC number: 271-678-5 | CAS number: 68603-87-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: sewage treatment simulation testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Justification for type of information:
- A read-across approach is taken from adipic acid, which is a structural analogue and serves as a good representation for the carboxylic acid mixture.
- Reason / purpose for cross-reference:
- read-across: supporting information
- Principles of method if other than guideline:
- Aerobic Sewage Treatment Simulation Test (Coupled-Units-Test ), comparable to OECD TG 303 A (Simulation Test-Aerobic Sewage Treatment. A: Activated Sludge Units)
- GLP compliance:
- no
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material:
PHYSICO-CHEMICAL PROPERTIES
- Melting point: 151°C (Rhodia Study, 2008)
- Boiling point: 337.5°C at 1013 hPa (Merck Index)
- Vapour pressure: 0.097 hPa at 18.5°C (Kirk-Othmer)
- Henry's law constant (for volatie substances): 9,656e-9 hPa m³/mol 25°C (Currenta, 2009)
- Water solubility: 23 g/L at 25°C (MITI, 1992)
- Solubility in organic solvents: Adipic acid is not stable in alcohol. The corresponding ester is formed (Beyer, 2004).
- log Pow: 0.093 at pH 3.3 (BASF-Study, 1988)
- pKa: 4.34-5.44 at 18°C; 4.43-5.42 at 20°C; 4.43 at 25°C (Beilstein, 2003)
- Base or acid catalysis of test material:
- UV absorption: t1/2 = 2,9d (Currenta, 2009)
OTHER PROPERTIES
- Adsorption characteristics: adsorption coefficient (Koc) 21.5 (Currenta, 2009)
- Toxicity to microorganisms: Activated sludge, 3-hour EC50 4747 mg/l (Bayer AG, 1988) - Radiolabelling:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Duration of test (contact time):
- 24 h
- Based on:
- DOC
- % Degr.:
- 99
- Parameter:
- DOC removal
- Sampling time:
- 1 d
- Transformation products:
- no
- Conclusions:
- In a waste water treatment simulation test a DOC removal of 99 % in 1 day was achieved.
- Executive summary:
In a waste water treatment simulation test (OECD TG 303 A "Simulation Test - Aerobic Sewage Treatment. A: Activated Sludge Units) a DOC removal of 99 % in 1 day was achieved.
- Endpoint:
- biodegradation in water: simulation testing on ultimate degradation in surface water
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Basic data given
- Justification for type of information:
- A read-across approach is taken from adipic acid, which is a structural analogue and serves as a good representation for the carboxylic acid mixture.
- Qualifier:
- according to guideline
- Guideline:
- other: OECD TG 302 B "Inherent biodegradability"
- Principles of method if other than guideline:
- modified Zahn-Wellens-Test
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material :
PHYSICO-CHEMICAL PROPERTIES
- Melting point: 151°C (Rhodia Study, 2008)
- Boiling point: 337.5°C at 1013 hPa (Merck Index)
- Vapour pressure: 0.097 hPa at 18.5°C (Kirk-Othmer)
- Henry's law constant (for volatie substances): 9,656e-9 hPa m³/mol 25°C (Currenta, 2009)
- Water solubility: 23 g/L at 25°C (MITI, 1992)
- Solubility in organic solvents: Adipic acid is not stable in alcohol. The corresponding ester is formed (Beyer, 2004).
- log Pow: 0.093 at pH 3.3 (BASF-Study, 1988)
- pKa: 4.34-5.44 at 18°C; 4.43-5.42 at 20°C; 4.43 at 25°C (Beilstein, 2003)
- Base or acid catalysis of test material:
- UV absorption: t1/2 = 2,9d (Currenta, 2009)
OTHER PROPERTIES
- Adsorption characteristics: adsorption coefficient (Koc) 21.5 (Currenta, 2009)
- Toxicity to microorganisms: Activated sludge, 3-hour EC50 4747 mg/l (Bayer AG, 1988) - Oxygen conditions:
- aerobic
- Inoculum or test system:
- natural water
- Details on source and properties of surface water:
- surface water of river Main
- Duration of test (contact time):
- 8 d
- Initial conc.:
- 997 mg/L
- Based on:
- COD
- Initial conc.:
- 345 mg/L
- Based on:
- DOC
- % Degr.:
- > 95
- Parameter:
- DOC removal
- Sampling time:
- 8 d
- Transformation products:
- not measured
- Conclusions:
- In a modified Zahn-Wellens test conducted with surface water of the river main 90 percent adipic acid was degraded after 7 days.
- Executive summary:
In a modified Zahn-Wellens test conducted with surface water of the river main 90 percent adipic acid was degraded after 7 days.
Referenceopen allclose all
Initial concentration not reported
Kinetic of test substance (in %):
ca. 10 after 1 day(s)
ca. 25 after 2 day(s)
ca. 40 after 3 day(s)
ca. 65 after 4 day(s)
> 90 after 7 day(s)
Description of key information
Carboxylic acids, di-, C4-6 is considered to be readily biodegradable in surface waters and waste water treatment plants.
Key value for chemical safety assessment
Additional information
For the mixture no data on biodegradation in surface water and sediment are available. Adipic acid is applied for read-across approach.
Adipic acid is shown to be biodegradable in surface waters and waste water treatment plants. In a modified Zahn-Wellens-Test, using surface water from the river Main (Germany), 90% of adipic acid was degraded within 8 days (Zahn, 1980).
A waste water treatment simulation test was performed according to a method which is comparable to the OECD guideline 303 A ("Simulation Test - Aerobic Sewage Treatment. A: Activated Sludge Units). Sludge from a municipal sewage treatment plant was used in this test. After 1 day a DOC removal of 99% was achieved (Gerike, 1979).
As it is shown that all constituents of the mixture are readily biodegradable, it is concluded that succinic acid and glutaric acid are also biodegradable in surface waters and waste water treatment plants.
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