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Diss Factsheets
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EC number: 701-480-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
Description of key information
Complex metal containing substance
Poor solubility in water
Transformation/dissolution tests and bio-accesability tests are more applicable to metals and are available from the Section 5.6 "Environmental fate and pathways -additional information on environmental fate" and Section 7.1.1 "Toxicological information - toxicokinetics"
Key value for chemical safety assessment
- at the temperature of:
- 30 °C
Additional information
Water solubility study according to OECD 105 was performed (Liipo, et all, 2010,Report 10081-ORC) The water solubility test method is intended for essentially pure substances and gives saturation mass concentration of the substance in water at a given temperature.
Given the fact that the tested material is complex low soluble metal containing substance, some uncertainties associated with the results were considered:
- For a complex substance, the measured solubility is dependent on the amount of test substance added. According to Guidance R7.A, p.87 test shall be performed at least two loadings rates 100 mg/l and 1000 mg/l).Water solubility in the study (Liipo, et all, 2010,Report 10081-ORC) was determined at high loading 5g/100 ml.Additional study on the effect of loading was performed (Karhu and Kinnunen,2010, Report 10059-ORC-T). Smaller sample size decreased analyzed soluble concentrations ( Cu <0.1 mg/l)
- The equilibration period was much longer than normal (14-16 days), therefore consideration has to be given to the possible breakdown of the test item during the extended test period (Guidance R7.A, p.87). The agitation of the flasks might cause abrasion and increase solubility. Additional study performed to determine the effect on agitation speed on the water solubility (Kinnunen, 2010, Report 10125-ORC-T). It has been shown that agitation of the flasks may cause abrasion and despite centrifugation, tiny particles may be included in the solution and cause increase of analysed concentration further interpreted as higher solubility. Water solubility of Cu, Ni, Zn, Pb, As in the range of <0.2 mg/l observed.
- When dealing with test substances with water low solubility precautions need to be taken to avoid the introduction of dispersed material into the final extract. Additional study performed to determine the effect on different parameters in the flask method(Karhu and Kinnunen, 2010, Report 10059-ORC-T). Filtration of the samples clearly decreased the water solubility results. This would suggest that agitation may rub off the surface of the test material and that these tiny particles were not completely settled down by centrifugation. Solubility of Cu in the range <0.2 mg/l observed for filtered samples (filter < 0.45 µm)
Given the uncertainties above copper slag was still slightly soluble in water solubility test performed after long agitation time of 14-16 days at high loading of 5g/100ml. Consideration of sample filtration , low loading and low stirring rate suggest water solubility of <0.2 mg/l
Transformation/dissolution (OECD, 2001) is more suitable for metals and sparingly soluble metal compounds (see IUCLID Section 5.6).The outcomes of the transformation/dissolution tests were used for aquatic classification
In vitro bio-accessibility tests were carried out to assess the solubility of metals in copper slag in extraction solvent that resembles gastric fluid (using HCl 0.07N at pH 1.5) in accordance with the ASTM D 5517-07 standard see IUCLID Section 7.1). The outcome of bio-elution test was used to support classification for human hazards.
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