Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
health surveillance data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2001

Materials and methods

Study type:
health record from industry
Endpoint addressed:
not applicable
Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
see Method - details on study design
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
N,N'-ethylenebis[N-acetylacetamide]
EC Number:
234-123-8
EC Name:
N,N'-ethylenebis[N-acetylacetamide]
Cas Number:
10543-57-4
Molecular formula:
C10H16N2O4
IUPAC Name:
N,N'-ethylenebis[N-acetylacetamide]

Method

Details on study design:
Approximately 200 workers in the Wiesbaden production plant and laboratory of Clariant have been monitored over the last 21 years. The employees have been examined in frequencies of one to two years since 1981. The examination included blood, lung function and ECG.

Results and discussion

Results:
At no time evidence of systemic, generalized or local reactions due to TAED have been found, especially no allergic reactions or skin irritations occurred.

Applicant's summary and conclusion