Registration Dossier
Registration Dossier
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EC number: 406-176-9 | CAS number: 79072-96-1 NC-4
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC50, Activated sludge > 1000 mg/L
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
An Activated Sludge Respiration Inhibition Test (ASRIT) was conducted (Huntingdon Life Sciences, OFX0010, 2011) to determine the acute effect of NC-4 on the respiration rate of activated sludge. The study was conducted according to EC test guideline C11, and in compliance with GLP.
Activated sludge from a source treating predominantly domestic waste was treated with test substance at 10, 30, 100, 300, and 1000 mg/L. NC-4 was considered to have had no significant inhibitory effect on the respiration rate of activated sludge at any of the concentrations employed in the test. The EC20, EC50, and EC80 of NC-4 could no be calculated but each of these must be greater than 1000 mg/L, the highest concentration tested.
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