Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 210-647-2 | CAS number: 620-67-7
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No effects up to the limit of water solubility (WS < 0.05 mg/L)
Key value for chemical safety assessment
Additional information
The chronic toxicity of propane-1,2,3-triyl trisheptanoate (CAS No. 620-67-7) to aquatic invertebrates has been evaluated by Schlechtriem (2012). This test was conducted according to OECD 211, under GLP conditions. Daphnia magna was exposed to the substance at a single loading rate (100 mg/L, limit test) for 21 days within a semi-static water regime. At the end of the exposure period, no effects on mobility, timing for reproduction (1st brood) or body length were reported. However, statistically significant differences between control and treatment group were observed regarding the number of cumulative offspring (inhibition effect of 15.5%). Therefore, the NOELR regarding reproduction could not be determined. Due to this fact,a new study according to OECD 211 was performed following the same methodology as the previous one, but using a lower test concentration (Schlechtriem (2013)).Daphnia magna was exposed to the substance at a single test concentration (1 mg/L, limit test) for 21 days within a semi-static water regime. No effects of the substance on survival, growth and reproduction were observed at the tested concentration, leading to a NOELR ≥ 1 mg/L (nominal loading rate).
Based on the above information, no chronic toxicity of propane-1,2,3-triyl trisheptanoate to aquatic invertebrates is expected up to the limit of its water solubility (WS < 0.05 mg/L).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
