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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

Description of key information

For both Bioaccumulation: aquatic / sediment endpoints 001 and 002, the study reports are no longer available. Study summaries are therefore provided for information purposes only.

Current versions of EPIWIN have not been validated for estimating endpoints that contain metals in their molecular structure; therefore, estimated values derived from the EPIWIN models should be used with caution. This is the case with Bioaccumulation: aquatic / sediment 003.

Therefore, no BCF value can be determined for tetrabutyltin.

Key value for chemical safety assessment

Additional information

Bioaccumulation: aquatic / sediment. 001

CERI.  2000

Common carp (Cyprinus carpio, ca. 30 g wet weight, ca. 10 cm length) were exposed to tetrabutyltin (TTBT) in a flow-through system for 84 days.   Fish were fed twice daily an amount generally corresponding to ca. 2 % of the total body weight.  TTBT is not soluble (<10 mg/L) in water, therefore, a solubilizer (not identified) was used. Tests were conducted at two concentration levels: 0.5 and 5 µg/L, with 15-20 fish tested at each level.  Water samples were analyzed twice-weekly and whole-body fish samples were analyzed every two weeks.  

Test conditions

- Flow rate = 200-800 mL/minute

- Temp. = 23-25 deg. C

- DO = 6-8 mg/L  

Fish lipid content was reported as 2 - 6 % (average = 3.8 %).

BCF values (0.5 ug/L): 127-310 (log BCF 2.10-2.49)

Bioaccumulation: aquatic / sediment. 002

CERI.  2000

Common carp (Cyprinus carpio, ca. 30 g wet weight, ca. 10 cm length) were exposed to tetrabutyltin (TTBT) in a flow-through system for 84 days. Fish were fed twice daily an amount generally corresponding to ca. 2% of the total body weight. TTBT is not soluble (<10 mg/L) in water, therefore, a solubilizer (not identified) was used. Tests were conducted at two concentration levels: 0.5 and 5 µg/L, with 15-20 fish tested at each level. Water samples were analyzed twice-weekly and whole-body fish samples were analyzed every two weeks. 

Test conditions:

- Flow rate = 200-800 mL/minute

- Temp. = 23-25 deg. C

-DO = 6-8 mg/L 

Fish lipid content was reported as 2 - 6% (average = 3.8 %).

BCF values (5 µg/L): 38-97 (log BCF 1.58-1.99)

Bioaccumulation: aquatic / sediment. 003

USEPA. 2000 (BCFWIN Version 2.15)

BCF value of 4017 L/kg (log BCF = 3.604) was estimated based on a measured log Kow of 5.07.