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Diss Factsheets
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EC number: 254-809-0 | CAS number: 40137-22-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Not stated
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted to internationally accepted guidelines (OECD 302 B). Report also contains QA statement and has been conducted according to GLP. Some details on the test substance were missing, eg purity, lot number.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 989
- Report date:
- 1989
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- 3-(methylamino)propane-1,2-diol
- EC Number:
- 254-809-0
- EC Name:
- 3-(methylamino)propane-1,2-diol
- Cas Number:
- 40137-22-2
- Molecular formula:
- C4H11NO2
- IUPAC Name:
- 3-(methylamino)propane-1,2-diol
- Reference substance name:
- methylaminopropandiol
- IUPAC Name:
- methylaminopropandiol
- Details on test material:
- - Name of test material (as cited in study report): methylaminopropandiol (MAPD)
- Physical state: Liquid
- Analytical purity: Not stated
- Lot/batch No.: Not stated
- Storage condition of test material: 5°C in the dark
Constituent 1
Constituent 2
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): secondary settlement tank from Rungsted sewage plant. This plant does not receive industrial sewage. The sludge was collected immediately prior to test set up.
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 80 mg/L
- Based on:
- DOC
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Not stated
- Test temperature: Not stated
- pH adjusted: yes (pH was daily adjusted to about 7.0 with 1N sodium hydroxide)
- Aeration of dilution water: Not stated
- Suspended solids concentration: 1.1 g solid per 1 mL (1g) test solution
- Continuous darkness: Not stated
TEST SYSTEM
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions: Not stated
- Test performed in open system: Not stated
SAMPLING
- Sampling frequency: 0 and 3 hours from start then on days 7, 14, 20 and 28.
- Sampling method: Not stated
- Sterility check if applicable: Not stated
- Sample storage before analysis: samples filtered through 0.45 um filter (cellulose nitrate) and frozen prior to analysis
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Abiotic sterile control: yes (microbial activity was stopped by applying 100 mg Mercury chloride per litre).
Reference substance
- Reference substance:
- diethylene glycol
Results and discussion
% Degradation
- Parameter:
- % degradation (DOC removal)
- Value:
- 94
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- inherently biodegradable
- Conclusions:
- The test compound MAPD was in the test ultimately degradable within 28 days .
MAPD was degraded by 94 percent of the initial concentration.
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