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EC number: 230-949-8 | CAS number: 7381-01-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Additional physico-chemical information
Administrative data
- Endpoint:
- other: Critical micelle concentration (CMC)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 16 July 2013 - 23 August 2013
- Reliability:
- other: not applicable.
- Rationale for reliability incl. deficiencies:
- other: Not a Reach requirement
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- The critical micelle concentration (CMC) of the test substance was determined since the test substance is surface active. For surface active substances which form micelles in solution, the surface tension decreases with increasing concentration until the CMC is reached. At concentrations above the CMC, the surface tension remains constant. The CMC was determined by measuring the surface tension of test substance solutions at different test substance concentrations. The concentrations were expressed as mg test substance/L (i.e. not corrected for purity). The surface tension measurements were performed using the OECD Harmonized ring method.
- GLP compliance:
- yes
Test material
- Reference substance name:
- Sodium 2-sulphonatoethyl laurate
- EC Number:
- 230-949-8
- EC Name:
- Sodium 2-sulphonatoethyl laurate
- Cas Number:
- 7381-01-3
- Molecular formula:
- C14H28O5S.Na
- IUPAC Name:
- sodium 2-sulphonatoethyl laurate
- Test material form:
- other: powder and needles
- Details on test material:
- - Name of test material (as cited in study report): Sodium Lauroyl Isethionate
- Description: White powder and needles
- Storage condition of test material: At room temperature in the dark, in well-sealed container
- Expiration date of the batch: 01 December 2014
- Hygroscopic: Yes
Constituent 1
Results and discussion
- Results:
- The plot of the surface tension of the test solutions as function of log C is shown below. The CMC was determined from the intersection of the two trendlines y1 and y2. Trendline y1 was obtained from the concentrations 1.00- 1009 mg/L. Trendline y2 was obtained from the concentrations 5006 - 25001 mg/L. The intersection was calculated to be log C = 3.42. It corresponded with a CMC of 2.6 g/L. It has to be noted that the CMC was above the water solubility (1.29 g/L: see endpoint 4.8 ) indicating that the CMC is likely influenced by minor components present in the test substance.
Any other information on results incl. tables
Surface tension measurements test solution 1.0 mg/L
Measurement |
Time passed [minutes] |
Surface tension [mN/m] |
||
individual |
mean |
mean corrected (1) |
||
1 |
15 |
74.0 |
||
2 |
16 |
74.1 |
74.0 |
75.5 |
3 |
16 |
73.9 |
||
4 |
17 |
74.1 |
||
5 |
18 |
74.0 |
(1) Multiplied by Φb followed by correction according to Harkins-Jordan.
Surface tension measurements test solution 10.1mg/L
Measurement |
Time passed [minutes] |
Surface tension [mN/m] |
||
individual |
mean1 |
mean corrected (2) |
||
1 |
16 |
61.9 |
||
2 |
16 |
62.0 |
68.6 |
69.9 |
3 |
17 |
63.0 |
||
4 |
18 |
64.1 |
||
5 |
19 |
64.4 |
||
6 |
19 |
68.5 |
||
7 |
20 |
68.6 |
||
8 |
21 |
68.8 |
||
9 |
22 |
68.4 |
||
10 |
23 |
68.6 |
(1) Mean calculated from measurements 6 to 10.
(2) Multiplied by Φb followed by correction according to Harkins-Jordan.
Surface tension measurements test solution 100.7 mg/L
Measurement |
Time passed [minutes] |
Surface tension [mN/m] |
||
individual |
mean |
mean corrected (1) |
||
1 |
15 |
56.1 |
||
2 |
15 |
55.9 |
55.9 |
56.0 |
3 |
16 |
56.0 |
||
4 |
17 |
55.8 |
||
5 |
17 |
55.9 |
(1) Multiplied by Φb followed by correction according to Harkins-Jordan.
Surface tension measurements test solution 10009.2 mg/L
Measurement |
Time passed [minutes] |
Surface tension [mN/m] |
||
individual |
Mean (1) |
Mean corrected (2) |
||
1 |
15 |
39.4 |
||
2 |
16 |
38.2 |
37.9 |
36.8 |
3 |
17 |
37.1 |
||
4 |
18 |
37.8 |
||
5 |
19 |
38.1 |
||
6 |
19 |
37.8 |
||
7 |
20 |
37.9 |
||
8 |
21 |
37.8 |
(1) Mean calculated from measurements 4 to 8.
(2) Multiplied byΦb followed by correction according to Harkins-Jordan.
Surface tension measurements test solution 5005.7 mg/L
Measurement |
Time passed [minutes] |
Surface tension [mN/m] |
||
individual |
Mean |
mean corrected (1) |
||
1 |
17 |
33.9 |
||
2 |
18 |
33.8 |
33.9 |
32.0 |
3 |
18 |
34.1 |
||
4 |
19 |
33.8 |
||
5 |
20 |
33.7 |
(1) Multiplied by Φb followed by correction according to Harkins-Jordan.
Surface tension measurements test solution 10007.5 mg/L
Measurement |
Time passed [minutes] |
Surface tension [mN/m] |
||
individual |
mean |
mean corrected (1) |
||
1 |
15 |
32.4 |
||
2 |
15 |
32.5 |
32.3 |
30.4 |
3 |
16 |
32.2 |
||
4 |
17 |
32.2 |
||
5 |
18 |
32.3 |
(1) Multiplied by Φb followed by correction according to Harkins-Jordan.
Surface tension measurements test solution 25001.0 mg/L
Measurement |
Time passed [minutes] |
Surface tension [mN/m] |
||
individual |
Mean (1) |
Mean corrected (2) |
||
1 |
16 |
33.8 |
||
2 |
17 |
34.0 |
32.1 |
30.2 |
3 |
18 |
31.9 |
||
4 |
19 |
32.2 |
||
5 |
19 |
31.8 |
||
6 |
20 |
32.1 |
||
7 |
21 |
32.3 |
(1) Mean calculated from measurements 3 to 7.
(2) Multiplied by Φb followed by correction according to Harkins-Jordan.
Applicant's summary and conclusion
- Conclusions:
- The critical micelle concentration CMC of the test substance was determined to be 2.6 g/L by measuring the surface tension of test substance solutions at different test substance concentrations.
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