N-amidinosarcosine

Explosiveness

Link to relevant study record(s)

Reference

Endpoint:

explosiveness, other

Remarks:

explosiveness of solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2012-02-10

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with generally accepted scientific standards and described in sufficient detail

Qualifier:

according to guideline

Guideline:

other: SOP SPZ-420

Principles of method if other than guideline:

With the differential scanning calorimetry the heat flow between the (filled) sample crucible and a reference crucible (filled with an inert material or left empty) is measured as a function of the oven temperature and of time.

GLP compliance:

not specified

Key result

Parameter:

other: Explosiveness (not specified)

Remarks on result:

negative (not further specified)

The result of the DSC test (temperature range 30 °C – 500 °C) showed an endothermic reaction starting at about 220 °C. The enthalpy was 514.4 J/g.

According the "Guidance on information requirements and chemical safety assessment Chapter R.7a: Endpoint specific guidance" testing should be carried out if the screening procedure identifies the material as having the potential to possess explosive properties, or there is any doubt. As the result of the DSC did only show an endotheric reaction at about 220°C the sample can be excluded from the hazard class “self-reactive substances” and testing does not need to be conducted.

Interpretation of results:

GHS criteria not met

Conclusions:

Creatine (anhydrous) is not considered to be an explosive.

Executive summary:

The substance Creatine (anhydrous) was tested to check for assignment to the physical hazard classes “self-reactive substances” to get information on the potential explosive properies of the substance. The result of the DSC test (temperature range 30 °C – 500 °C) showed an endothermic reaction starting at about 220 °C. The enthalpy was 514.4 J/g.

According the "Guidance on information requirements and chemical safety assessment Chapter R.7a: Endpoint specific guidance" testing should be carried out if the screening procedure identifies the material as having the potential to possess explosive properties, or there is any doubt. As the result of the DSC did only show an endotheric reaction at about 220°C the sample can be excluded from the hazard class “self-reactive substances” and testing on explosiveness does not need to be conducted.

The result of the differential scanning calorimetry described indicates that the substance is not explosive as there is no exothermic decomposition energy more than 500 J/g and hence no onset of exothermic decomposition below 500ºC.

Therefore, Creatine (anhydrous) is not considered to be an explosive.

Description of key information

The result of the differential scanning calorimetry conducted indicates that Creatine (anhydrous) is not an explosive

as there is no exothermic decomposition energy more than 500 J/g and hence there is no onset of exothermic decomposition below 500ºC.

Key value for chemical safety assessment

Explosiveness:

non explosive

Additional information

A differential scanning calorimetry with Creatine (anhydrous) was conducted to get information on the potential explosive properies of the substance. The result of the DSC test (temperature range 30 °C – 500 °C) showed an endothermic reaction starting at about 220 °C. The enthalpy was 514.4 J/g. Therefore, Creatine (anhydrous) is not considered to be an explosive.

Justification for classification or non-classification

According the results of the differential scanning calorimetry Creatine (anhydrous) is considered to be not an explosive and does not have to be classified.