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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Dissociation constant
Administrative data
Link to relevant study record(s)
Description of key information
The UVCB substance 400160 consists of diester, monoester, and the diacid component. Out of these three components only the diacid and monoester are able to dissociate. The pKa of the diacid component is comparable to those of other long-chain fatty acids, e.g. oleic acid (calculated pKa 4.74 - SPARC On Line-Calculator, pKa 5.02 - literature value).
Key value for chemical safety assessment
Additional information
400160 is a surface active UVCB substance. For complex mixtures (e.g. UVCBs) containing ionisable components the assessment of pKa is technically challenging. The analytical method is not sensitive enough. As the analytical effort and costs to measure the dissociation constant of 400160 are not justified a weight of evidence approach was used instead of testing. Therefore the estimation of the ionisable component was considered.
The dissociation constant of the diacid component is similar to those of other long-chain fatty acids, e.g. oleic acid (pKa = 4.74 calculated for oleic acid using SPARC On-Line Calculator; pKa = 5.02 in aqueous solution at 25°C – literature value).
The compounds of 400160 which are able to dissociate have a pKa of around 5. Therefore the predicted pKa value matches the lower level of the environmental relevant pH margin (pH 5 -9). It is not expected that the predicted pKa value significantly differs from that value that could be obtained by testing.
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