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EC number: 206-490-4 | CAS number: 349-76-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16 Oct to 05 Nov 1996
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- other: US Federal Register 40 CFR Part 796.1840
- GLP compliance:
- yes
- Type of method:
- flask method
- Water solubility:
- 622.8 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 8.1 g/L
- Incubation duration:
- 3 d
- Temp.:
- 25 °C
- pH:
- 7.78
- Remarks on result:
- other: centrifugation: 30000 G
- Water solubility:
- 631.7 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 7.91 g/L
- Incubation duration:
- 2 d
- Temp.:
- 25 °C
- pH:
- 7.76
- Remarks on result:
- other: centrifugation: 30000 G
- Water solubility:
- 620.8 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 7.92 g/L
- Incubation duration:
- 1 d
- Temp.:
- 25 °C
- pH:
- 7.73
- Remarks on result:
- other: centrifugation: 30000 G
- Water solubility:
- 608.4 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 7.98 g/L
- Incubation duration:
- 3 d
- Temp.:
- 25 °C
- pH:
- 7.83
- Remarks on result:
- other: centrifugation: 50000 G
- Water solubility:
- 599.6 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 8.11 g/L
- Incubation duration:
- 2 d
- Temp.:
- 25 °C
- pH:
- 7.74
- Remarks on result:
- other: centrifugation: 50000 G
- Water solubility:
- 615.2 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 8.02 g/L
- Incubation duration:
- 1
- Temp.:
- 25 °C
- pH:
- 7.67
- Remarks on result:
- other: centrifugation: 50000 G
- Details on results:
- The average of the water solubility was determined as 620 mg/L at 25 °C.
- Conclusions:
- The test item has a water solubility of 620 mg/L at 25 °C, pH ca. 7.7
- Executive summary:
A study was conducted to assess the water solublility of the test substance in accordance to OECD guideline number 105, the EC method A.6 and the US Federal Register 40 CFR Part 796.1840 using the "flask method".
On each of the first three days of the main experiment two test dispersions, each containing about thirteen times tbe amount of test substance necessary for saturation, were prepared in stainless steel centrifuge tubes and equilibrated by continuous shaking at 30.0 °C (± 0.1 °C) in a thermostatically controlled water bath. On the fourth day the temperature of the water bath was reduced to 25.0 °C (± 0.1 °C), at which temperature the six test dispersions were then shaken for a further 24 hours. The centrifuge tubes were tbeit centrifuged for 40 minutes at 30000 G or 50000 G in a thermostated centrifuge (25 °C). Subsequently, an aliquot from each clear, saturated solution was removed and analysed by high petfonnancc liquid chromatography (HPLC).
The water solubility of the test substance was determined as 620 mg/L at 25 °C, pH ca. 7.7.
Reference
Description of key information
A study was conducted to assess the water solublility of the test substance in accordance to OECD guideline number 105, the EC method A.6 and the US Federal Register 40 CFR Part 796.1840 using the "flask method".
On each of the first three days of the main experiment two test dispersions, each containing about thirteen times tbe amount of test substance necessary for saturation, were prepared in stainless steel centrifuge tubes and equilibrated by continuous shaking at 30.0 °C (± 0.1 °C) in a thermostatically controlled water bath. On the fourth day the temperature of the water bath was reduced to 25.0 °C (± 0.1 °C), at which temperature the six test dispersions were then shaken for a further 24 hours. The centrifuge tubes were tbeit centrifuged for 40 minutes at 30000 G or 50000 G in a thermostated centrifuge (25 °C). Subsequently, an aliquot from each clear, saturated solution was removed and analysed by high petfonnancc liquid chromatography (HPLC).
The water solubility of the test substance was determined as 620 mg/L at 25 °C, pH ca. 7.7.
Key value for chemical safety assessment
- Water solubility:
- 620 mg/L
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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