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EC number: 239-888-1 | CAS number: 15790-07-5 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 15985:1.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Based on the prediction done using the OECD QSAR toolbox version 3.3 with log kow as the primary descriptor and considering the six closest read across substances, toxicity on daphnia magna was predicted for aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]- 2-naphthalenesulfonic acid complex (15790-07-5). The EC50 value was estimated to be 83.527 mg/l when aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex exposed to daphnia magna for 504 hrs. Thus based on the EC50 it can be concluded that the chemical was nontoxic and can be consider to be not classified as per the CLP classification criteria.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 83.527 mg/L
Additional information
Based on the various predicted data for the target chemical and experimental data for read across chemicals study have been reviewed to determine the toxic nature of target chemical aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex (15790-07-5). The studies are as mentioned below:
In the first weight of evidence study for the target chemical (15790-07-5) toxicity was predicted based on the prediction done using the OECD QSAR toolbox version 3.3 with log kow as the primary descriptor and considering the six closest read across substances, toxicity on daphnia magna was predicted for aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]- 2-naphthalenesulfonic acid complex (15790-07-5). The EC50 value was estimated to be 83.527 mg/l when aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex exposed to daphnia magna for 504 hrs. Thus based on the EC50 it can be concluded that the chemical was nontoxic and can be consider to be not classified as per the CLP classification criteria.
In the second weight of evidence study for the read across chemical (657-84-1) from J-check study on determination of the inhibition of the mobility of daphnids was carried out with the substance Aluminium,6-hydroxy-5- [(2-methoxy-5-methyl-4-sul fophenyl)azo ]-2-naphthalenesulfonic acid complex according to OECD Guideline 211. Acute Immobilization Test of 4-methylbenzenesulfonic acid (Sodium p-toluenesulfonate) to Daphnia magna was studied for 21 days. Test was performed according to the OECD Guideline 211 (Daphnia magna Reproduction Test). Test performed in the semi-static system. Control, 100, 32, 10 mg/L nominal concentration was added in the test vessel filled with 80 ml of test solution. Test conducted in the ten replicates, 10 daphnia magna per concentration (1 per vessel was added). Based on the effect of chemical 4-methylbenzenesulfonic acid (Sodium p-toluenesulfonate) on the normal activity of daphnia magna for the 21 days, the EC50 was ≥ 100 mg/l and NOEC was 100 mg/l. Thus based on the EC50, it can be concluded that the 4-methylbenzenesulfonic acid was nontoxic and can be consider to be not classified as per the CLP classification criteria.
Similarly third weight of evidence study supports the first predicted study for RA chemical (5281-04-9) from OECD SIDS report, 1994 similar to the target chemical. Study was conducted to determine the long term toxicity of calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoate on the mortality rate of daphnia magna. Test conducted in the open system by semi-static method. 4 replicates were used in which 10 organisms were used in each replicates. Control of DMSO: HCO-40 was 9:1 (100 mg/kg). Test conducted on the nominal concentration for 7 days, 14 days and 21days. After the exposure of chemical lethal concentration was measured. Based on the mortality rate of daphnia magna due to the long period exposure with chemical calcium 3-hydroxy-4-[(4-methyl-2 sulfonatophenyl) diazenyl]-2-naphthoate, the LC50 value was 13 mg/l, 10 mg/l and 9.7 mg/l for 7 days, 14 days and 21 days of exposure. The EC50 was 4.4 and 9.1 after 14 and 21 days of exposure. Based on the LC50, it can be concluded that the chemical was nontoxic and not classified as per the CLP classification criteria.
Based on the data from various data, it can be concluded that the substance aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex (15790-07-5) is considered to be not toxic to aquatic environment and cannot be classified as toxic as per the criteria mentioned in CLP regulation.
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