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Diss Factsheets
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EC number: 218-849-2 | CAS number: 2253-52-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2003
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 003
- Report date:
- 2003
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: DS/EN ISO 14669 (1999)
- GLP compliance:
- no
Test material
- Reference substance name:
- O,O-diisobutyl hydrogen dithiophosphate
- EC Number:
- 218-849-2
- EC Name:
- O,O-diisobutyl hydrogen dithiophosphate
- Cas Number:
- 2253-52-3
- Molecular formula:
- C8H19O2PS2
- IUPAC Name:
- O,O-diisobutyl hydrogen dithiophosphate
- Test material form:
- other: Liquid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations:(nominial) 0, 2, 5, 10, 20, 50, 100 and 200 mg/l
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- other aquatic crustacea: Acartia tonsa (DANA)
- Details on test organisms:
- TEST ORGANISM
- Common name: Calanoid copepod (marine)
- Strain: Kept in culture at DHI since 1987, originally collected in the North Sea by Danmarks Fiskeriundersøgelser
Study design
- Test type:
- static
- Water media type:
- saltwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 19 ± 0.5 ºC
- pH:
- 8.0 ± 0.2
- Dissolved oxygen:
- ≥ 4 mg/l at test end
- Salinity:
- 33 ‰
- Nominal and measured concentrations:
- Nominal concentrations: 0, 2, 5, 10, 20, 50, 100 and 200 mg/
- Details on test conditions:
- TEST SYSTEM
- Test vessels: 50 ml glass beakers with approx. 25 ml of test soulution
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 6
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Natural seawater, filtered, collected in the North Sea near Hirtshals by Danmarks Fiskeriundersøgelser 26.10.2009
OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: 16:8 (light:dark) - Reference substance (positive control):
- yes
- Remarks:
- 3,5-dichlorophenol, CAS No.: 591-35-5
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 200 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Duration:
- 48 h
- Dose descriptor:
- LC10
- Effect conc.:
- > 200 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Results with reference substance (positive control):
- - Results with reference substance valid? Yes
- Mortality: in controls 13% (4 out of 31) which is higher than the recommended <10%. This is not considered to have had significant influence on the test systems sensitivity.
- LC50: 1.64 mg/l (a little higher than validation criterium, but not considered to have had significant influence on the test systems sensitivity.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- LC50(48 h) is > 200 mg/L for Acatia tonsa.
Control group mortality was a little higher than validation criterium, but this is not considered to have had significant influence on the test result.
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