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EC number: 256-283-8 | CAS number: 46830-22-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 29/09/1993-06/10/1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Well documented report of a guideline study conducted to GLP.
Data source
Reference
- Title:
- Unnamed
- Year:
- 1 994
- Report date:
- 1994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Benzyldimethyl[2-[(1-oxoallyl)oxy]ethyl]ammonium chloride
- EC Number:
- 256-283-8
- EC Name:
- Benzyldimethyl[2-[(1-oxoallyl)oxy]ethyl]ammonium chloride
- Cas Number:
- 46830-22-2
- Molecular formula:
- C14H20NO2.Cl
- IUPAC Name:
- benzyldimethyl[2-(prop-2-enoyloxy)ethyl]azanium chloride
- Details on test material:
- - Name of test material (as cited in study report): ADAMQUAT BZ 80,
- Physical state: liquid,
- Analytical purity: 78.5%.
- Impurities (identity and concentrations): not specified
- Composition of test material, percentage of components: 100%
- Purity test date: not specified
- Lot/batch No.: OP/611/613/615/616
- Expiration date of the lot/batch: not specified
- Stability under test conditions: stable
- Storage condition of test material: at room etmperature and away from the light
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- The initial solution of ADAMQUAT BZ 80 at 1 g/l was prepared the same day of the test.
DILUTION WATER: was prepared in the laboratory using pure water and salts according to ISO 6341.
For one litre: 25 ml of the below solutions
1- 11.76g CaCl2,2H2O/l ultrapure water.
2- 4.93g MgSO4,7H2O/l ultrapure water.
3- 2.59g NaHCO3/l ultrapure water.
4- 0.23g KCl/l ultrapure water.
- Aeration: aerated up until oxygen saturation.
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Strain: Daphnia magna.
- Source: Breeding colony was realized in the laboratory in ASTM medium, organisms were selected by sieving.
- Age at study initiation (mean and range, SD): : Less than 24 hours
- Weight at study initiation (mean and range, SD):
- Length at study initiation (length definition, mean, range and SD):
- Valve height at study initiation, for shell deposition study (mean and range, SD):
- Peripheral shell growth removed prior to test initiation:
- Method of breeding:
- Feeding during test
- Food type: Microscopic algae Selenastrum capricornutum
- Amount:
- Frequency:
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- Not specified
- Test temperature:
- 20±1°C
- pH:
- Not specified
- Dissolved oxygen:
- >2 mg/l.
- Nominal and measured concentrations:
- Nominal: 6, 10, 20, 30, 50, 60, 100 mg/l.
- Details on test conditions:
- TEST SYSTEM
- Test vessel:
- Type (delete if not applicable): open
- Material, size, headspace, fill volume: Glass tube (I=180mm, d =
- Aeration: No
- Renewal rate of test solution (frequency/flow rate): No
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water:was prepared in the laboratory using pure water and salts according to ISO 6341.
For one litre: 25 ml of the below solutions
1- 11.76g CaCl2,2H2O/l ultrapure water.
2- 4.93g MgSO4,7H2O/l ultrapure water.
3- 2.59g NaHCO3/l ultrapure water.
4- 0.23g KCl/l ultrapure water.
- Aeration: aerated up until oxygen saturation.
OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod:Incubation of test flasks in darkness.
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : The percentage of daphnids immobilisation after 24 and 48 hours.
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 44 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 24-79 mg/l
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- 6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 61 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 38-98 mg/l)
- Duration:
- 24 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- Quality criteria: Concentration of dissolved oxygen in the test vessels remained above 2mg/l at the end of the test. -Immobilisation in the control did not exceed 10% at the end of the test.
- Conclusions:
- The EC50 of ADAMQUAT BZ 80 to Daphnia magna at 48 hours is 44 mg/l.
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