Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 212-201-2 | CAS number: 768-94-5
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: peer reviewed data/database
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Journal of Medicinal Chemistry, vol. 49, # 24 p. 6958 - 6971
- Author:
- Hollosy, Ferenc; Valko, Klara; Hersey, Anne; Nunhuck, Shenaz; Keri, Gyoergy; Bevan, Chris
- Year:
- 2 006
- Bibliographic source:
- REAXYS, Registry No.2204333, 2011-03-17
- Reference Type:
- publication
- Title:
- Journal of Medicinal Chemistry, vol. 49, # 23 p. 6660 - 6671
- Author:
- Skoeld, Christian; Winiwarter, Susanne; Wernevik, Johan; Bergstroem, Fredrik; Engstroem, Leif; Allen, Ruth; Box, Karl; Comer, John; Mole, Jon; Hallberg, Anders; Lennernaes, Hans; et al.
- Year:
- 2 006
- Bibliographic source:
- REAXYS Regisry No.2204333, 2011-03-17
- Reference Type:
- publication
- Title:
- Journal of the American Chemical Society, vol. 122, # 3 p. 466 - 473
- Author:
- Jasys, V. John; Lombardo, Franco; Appleton, Troy A.; Bordner, Jon; Ziliox, Martine; Volkmann, Robert A.
- Year:
- 2 000
- Bibliographic source:
- REAXYS Registry No.2204333, 2011-03-17
Materials and methods
Test guideline
- Guideline:
- other: measured
- GLP compliance:
- not specified
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Amantadine
- EC Number:
- 212-201-2
- EC Name:
- Amantadine
- Cas Number:
- 768-94-5
- Molecular formula:
- C10H17N
- IUPAC Name:
- adamantan-1-amine
- Details on test material:
- Name of test material (as cited in study report): adamantan-1-amine
Analytical purity: pure
Constituent 1
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 2 - 2.47
Any other information on results incl. tables
Value from peer reviewed Database. No data available for temperature and pH value.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
