Registration Dossier
Registration Dossier
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EC number: 240-914-9 | CAS number: 16881-77-9
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- Dimethoxymethylsilane
- Type of composition:
- boundary composition of the substance
- State / form:
- liquid
- Reference substance:
- Dimethoxymethylsilane
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The PBT Assessment is based on the criteria set out in the “Guidance on information requirements and chemical safety assessment, Chapter R.11: PBT Assessment” (ECHA, 2017).
Persistence (P) Assessment
Dimethoxy(methyl)silane is expected to hydrolyse rapidly in contact with water to the stable silanol hydrolysis product methylsilanetriol and the alcohol hydrolysis product methanol (predicted DT50 = 0.3 h). A reliable ready biodegradation study (read-across) is available, which indicates that no significant biodegradation can be expected for the silanol hydrolysis product. Therefore, the hydrolysis product meets the screening criteria for persistence and the substance is concluded to be “vP (and P)”.
Bioaccumulation (B) assessment
Dimethoxy(methyl)silane is expected to hydrolyse rapidly in contact with water to methylsilanetriol and methanol (predicted DT50 = 0.3 h). Furthermore, the parent substance as well as the hydrolysis product methylsilanetriol have low log Kow values of 1.4 and -2.4, respectively. Therefore, the substance does not meet the screening criterion for bioaccumulation (< 3.0) and it is concluded to be “not B/vB”.
Toxicity (T) assessment
The lowest effect value for long-term toxicity is a NOEC (21 d) of ≥ 10 mg/L for aquatic invertebrates. Furthermore, the substance is not classified for mammalian toxicity (carcinogenic, mutagenic, toxic for reproduction, chronic toxicity or specific organ toxicity after repeated exposure). Therefore, the substance does not meet the screening criterion for T and it is concluded to be “not T”.
Overall conclusion
The substance is not PBT/vPvB
Reference
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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