Registration Dossier
Registration Dossier
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EC number: 231-869-6 | CAS number: 7773-01-5
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 06 June 2012 - 06 June 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study performed according to guideline and GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- sieving
Test material
- Reference substance name:
- Manganese dichloride
- EC Number:
- 231-869-6
- EC Name:
- Manganese dichloride
- Cas Number:
- 7773-01-5
- Molecular formula:
- Cl2Mn
- IUPAC Name:
- manganese(2+) dichloride
- Details on test material:
- - Name of test material (as cited in study report):MnCl2 flakes
- Physical state: light pink solid flakes
- Lot/batch No.: 104896-05
- Storage condition of test material: room temperature in the dark
Constituent 1
Results and discussion
Particle size distribution at different passages
- No.:
- #1
- Size:
- < 100 µm
- Distribution:
- 3.87 %
Any other information on results incl. tables
The results of the sieving procedure are shown in the following table:
Measurement |
Result |
Mass of test item transferred to sieve |
11.62 g |
Mass of test item passed through sieve |
0.45 g |
Proportion of test item < 100 µm |
3.87 % |
The inhalable fraction is defined as the mass fraction of particles which can be inhaled by nose or mouth, the thoracic fraction is defined as the mass fraction of particles that passes the larynx and the respirable fraction is defined as the mass fraction of particles that reaches the alveoli.
Since less than 10% of the test item had a particle size of less than 100 µm the test item is deemed to be essentially non-inhalable.
Applicant's summary and conclusion
- Conclusions:
- The proportion of test item having an inhalable particle size of less than 100 µm was determined to be 3.87 %. The test item has been considered to be essentially non-inhalable.
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