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EC number: 229-129-2 | CAS number: 6416-66-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Adequate chronic toxicity data are not available for the substance, therefore the aquatic toxicity assessment and classification are based mainly on the short-term toxicity data available.
Despite the substance has a log Kow lower than 4 (indicating a low potential for bioaccumulation), it is not rapidly (bio)degradable.
According to the CLP Regulation (EC 1272/2008), acute aquatic toxicity is normally determined using a fish 96-hour LC50 , a crustacean species 48-hour EC50 and/or an algal species 72- or 96-hour EC50; nevertheless it is also specified in the Regulation that data on other species (e.g. Lemna) shall also be considered if the test methodology is suitable.
Fish
The determination on ecotoxicity of the substance on Zebra fish has been performed in an acute test.
The study has no indication of the method used and there are not enough information to establish if all requirements of an international accepted method are fulfilled, nevertheless the study can be considered valid.
The LC50 is > 300 mg/l at 96 hours. This result is in agreement with studies performed on similar substances.
Invertebrates
The determination on ecotoxicity of the substance was determined in an acute test on Daphnia, according to the guideline 92/69/EEC C.2. The test substance was tested on Daphnia magna Straus 1820 for 48 hours.
20 daphnids (0-24 hours old) were exposed to nominal concentrations of 2.0, 4.4, 9.6,21,46 and 100 mg test substance respectively.
The EC 50 calculated at 48 hours resulted 104 mg/l.
Lemna
The inhibitory effects based on the average specific growth rate and the yield (absolute increase in plant size) to the duckweed Lemna minor was
investigated over a period of 7 days.
The test was performed at nominal concentrations of 11.4, 114 and 1140 mg/l of test substance, corresponding to 10, 100 and 1000 mg/l of the active ingredient (AI).
The no-observed-effect concentrations to Lemna minor with respect to growth rate (NOErC) and yield (NOEyC) for the endpoint frond number were 10
and <10 mg/l nominal concentration, respectively, as determined by Dunnett's test. Moreover, the median effect concentrations to Lemna minor with respect to growth rate (ErC50) and to yield (EyC50) for the endpoint dry weight was estimated to be about 100 – 1000 and about 100 mg/l nominal concentration, respectively.
Microorganism
A non detailed study is available. Toxicity on STP activated sludge has been performed. The result BST was > 300 mg/l.
In conclusion, the substance is not classified for aquatic toxicity because it doesn't meet the classification criteria of the CLP Regulation n. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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