Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 258-061-6 | CAS number: 52636-67-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of morpholinium sulphamate to algae was assessed according to OECD TG 201 and EU method C.3. The 72-h EC50 value based on growth rate and yield was determined to be greater than 100 mg/L. The 72-h NOEC based on growth rate and yield was determined to be greater than 100 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 100 mg/L
- EC10 or NOEC for freshwater algae:
- 100 mg/L
Additional information
The purpose of this study was to determine the effect of morpholinium sulphamate on the growth of a unicellular green algal species Pseudokirchneriella subcapita according to OECD Guideline No 201 and EU Method C.3. Based on the results of the preliminary test, the test item has no toxic effect on algae up to at least the concentration of 100 mg/L. Therefore a limit test was performed using only this concentration level and a control in order to demonstrate that the test item has no influence on the growth of algae up to at least this test concentration. The algal growth in relation to a control culture was determined over a fixed test period of 72 hours and thus, over several algal generation The results of the statistical evaluation showed that the 0-72 h average specific growth rate and yield at the treatment group (100 mg/L) was not statistically significantly different from the untreated control. Accordingly, the No Observed Effect Concentration (NOEC) was determined as100 mg/L. The 72-h EC10 and EC50 values based on growth rate and yield were determined to be higher than 100 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
