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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Description of first aid measures
Inhalation
After inhalation move to fresh air. If shortness of breath occurs, support respiration and consult a physician.
Bring patient immediately to fresh air. If breathing is heavily give oxygen; if necessary respirate artificially. Call physician.
Consult a physician if irritating symptoms develop and persist.
Skin Contact
Remove contaminated clothing. Rinse contaminated skin immediately with plenty of water and soap and seek medical advice.
Eye Contact
Immediately rinse eyes thoroughly with running water as long as possible (approx. 15 min). Take injured quickly to factory medical center or call an ambulance (code word: eye accident).
Ingestion
Do not induce vomiting. In case of consciousness wash mouth with water and let drink some of water.
Seek medical advice. Keep patient at rest. If swallowed, seek medical advice immediately and show this container or label.
Indication of any immediate medical attention and special treatment needed
Notes to Physician
Apply general supportive and symptomatic treatment.
Fire-fighting measures
Extinguishing media
Suitable Extinguishing Media
Water spray or fog Foam Fire-extinguishing powder carbon dioxide (CO2)
Unsuitable Extinguishing Media
High volume water jet
Special hazards arising from the substance or mixture
Dangerous Combustion Products
hydrogen chloride
Hydrofluoric acid (hydrogen fluoride)
nitrogen oxides
carbon oxides
Advice for firefighters
Protective equipment for firefighters
Wear self-contained breathing apparatus and fire protective suite
Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal precautions Wear chemical resistant protective suite. Do not proceed against the wind direction. Keep away unprotected persons.
Environmental precautions
Do not release on the soil or into drains. Neutralization is normally necessary before a waste water is discharged into sewage treatment plants.
Methods and material for containment and cleaning up
Wash away remains with plenty of water. Transfer or pump large quantities into a container.
Handling and storage
Precautions for safe handling
Storage and Handling Precautions
Keep container tightly closed in a dry, cool and well-ventilated place. Ensure efficient exhaust ventilation when using this product.
Conditions for safe storage, including any incompatibilities
Technical measures/Precautions
Handle product only in closed system or provide appropriate exhaust ventilation at machinery.
Preventive Precautions (fire/explosion)
Take precautionary measures against static discharges. Avoid formation of dust. Observe the usual precautionary measures required for chemicals with dust explosive properties (Observe national regulations). Keep away from open flames, hot surfaces and sources of ignition.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 1759
Shipping information
- Proper shipping name and description:
- Corrosive solid, n.o.s.
(Contains: Quinoline derivative) - Chemical name:
- 2-Fluoro-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzoic acid hydrochloride
(1:x) - Language:
- English
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 1759
Shipping information
- Proper shipping name and description:
- Corrosive solid, n.o.s.
(Contains: Quinoline derivative) - Chemical name:
- 2-Fluoro-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzoic acid hydrochloride
(1:x)
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 1759
Shipping information
- Proper shipping name and description:
- Corrosive solid, n.o.s.
(Contains: Quinoline derivative) - Chemical name:
- 2-Fluoro-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzoic acid hydrochloride
(1:x)
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Industrial Hygiene
The personal protective measure may be adapted appropriately when working in closed systems or under laboratory conditions.
Regular cleaning of equipment, work area and clothing.
No open handling without using reliable equipment. One technical barrier between substance and employee resp. environment.
Restricted and controlled access for trained personnel only.
Designated washing, changing and shower facilities must be available.
Internal working procedures available to personnel covering personal hygiene, decontamination / cleaning, consideration of worst case incidents, spills, emergency, alarms, waste disposal and maintenance.
Personnel comprehensively instructed, highly trained and experienced. Regular refresher training
established including appropriate record keeping.
Equipment and protective garments must either be decontaminated or properly contained for disposal before leaving the area.
Disposable protective equipment is to be decontaminated before removal (decontamination shower).
Open Handling Respiration : Full face mask (EN136)
Filter : P3 (EN143)
Eye : Yes, by face mask
Hand : Normal length chemical-mechanical-resistant gloves (EN374/EN388)
worn over disposable gloves
Glove Material : Nitrile
Breakthrough time: 240 min
Thickness: 0.4 mm
Additional protection : Disposable dust-proof suit (EN465, type 4) worn over long underwear Disposable
boot covers, conductive
Stability and reactivity
Drop-Weight Test: Negative
Deflagration: No suspect of deflagration based on thermal data
Explosivity by shock: Negative
Method: SWISSI PROCESS SAFETY GMBH
Deflagration: No suspect of deflagration based on thermal data
Dust Explosion Positive
Method: modified Hartmann tube
Minimum Ignition Energy: 100 - 300 mJ
Method: MIKE3 (minimal ignition energy test without inductance)
Positive
Method: modified Hartmann tube
Minimum Ignition Energy: 100 - 300 mJ
Method: MIKE3 (minimal ignition energy test without inductance
Disposal considerations
Waste treatment methods
Disposal Requirements Incineration in an approved, controlled furnace with combustion gas scrubbing
and emission gas control.
Container Disposal
For disposal local regulation is binding.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.