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Diss Factsheets

Physical & Chemical properties

Density

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
tap density
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental test results performed using standard test guidelines.
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
GLP compliance:
no
Type of method:
pour and tap (for solids)
Key result
Type:
tap density
Density:
0.73 g/cm³
Temp.:
20 °C
Key result
Type:
pour density
Density:
0.616 g/cm³
Temp.:
20 °C

Observations 












































































Sr No.



Parameters



Observations



1st  Observation



2nd Observation



1



Test  temperature(°C)



 



20



20



2



Atmospheric pressure (in hPa)



962.6



962.1



3



Weight of test chemical (m)



92.474 g



92.470 g



4



Volume of measuring cylinder; readability in g



250 mL;2 g



250 mL;2g



5



Volume of test chemical in cylinder without tapping (v)



150 mL



150 mL



6



Volume of test chemical in cylinder after tapping (v1)



After 10 tapping



132 mL



134 mL



After 50 tapping



120 mL



122 mL



After 100 tapping



120 mL



122 mL



After 250 tapping



0



0



After 500 tapping



0



0



After750 Tapping



0



0



CALCULATIONS


The density of the test chemical using the formula:


For water soluble solids:


Where, m= mass of the test chemical


             v= volume of the test chemical


 






























               Parameters



         Details



           Calculated values



Average Density



1st  Calculation



2nd Calculation



Pour  Density of test Item (g/cm3)



m
     v



0.6160



0.6160



0.616



Tap density of test Item (g/cm3)



m
    v1



0.7010



0.7580



0.730


Conclusions:
The mean pour density and tapped density of test chemical was determined to be 0.616 g/cm3 and 0.730 g/cm3 at 20 °C and 962.4 hPa.
Executive summary:

A study was performed to determine the density of test chemical in respective atmospheric pressure and temperature conditions.


The study was conducted in accordance with OECD guideline for the Testing of Chemicals no. 109; Density of Liquid and Solids, Adopted: 2 October 2012 and Adopted from method recommended in the International Pharmacopoeia, fourth Edition, 2014


The mean pour density and tapped density of test chemical was determined to be 0.616 g/cm3 and 0.730 g/cm3 at 20 °C and 962.4 hPa.

Description of key information

The mean pour density and tapped density of test chemical was determined to be 0.616 g/cm3 and 0.730 g/cm3 at 20 °C and 962.4 hPa.

Key value for chemical safety assessment

Additional information

A study was performed to determine the density of test chemical in respective atmospheric pressure and temperature conditions.


The study was conducted in accordance with OECD guideline for the Testing of Chemicals no. 109; Density of Liquid and Solids, Adopted: 2 October 2012 and Adopted from method recommended in the International Pharmacopoeia, fourth Edition, 2014


The mean pour density and tapped density of test chemical was determined to be 0.616 g/cm3 and 0.730 g/cm3 at 20 °C and 962.4 hPa.