Registration Dossier
Registration Dossier
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EC number: 458-610-1 | CAS number: 60466-73-1
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Aquatic toxicity
One valid acute experimental study on Danio rerio and two QSAR predictions are available to assess the aquatic toxicity of the registered substance.
The most sensitive organism appears to be the algae with a predicted 72h-ErC50 of 18 mg/L, followed by daphnids with a predicted 48h-EC50 of 19 mg/L. Fish are slightly less sensitive with a 96h-LC50 of 20.1 mg/L.
Environmental fate and pathways
According to the key biodegradation study (OECD Guideline 301F, EU Method C.4-D, GLP), the registered substance is not considered as readily biodegradable (44% biodegradation after 28 days) and therefore the criterion of rapid degradability is not met, according to CLP Regulation No 1272/2008. Nevertheless, significant mineralisation occurred thus demonstrating complete primary biodegradation, and based on the enhanced screening test, extended up to 49 days (62% biodegradation after 49 days), the registered substance is not considered persistent in the environment.
The registered substance has a log Kow value of 3.0 (20 °C), consequently the substance is not considered to be bioaccumulative according to CLP (< 4.0) and PBT criteria (< 4.5).
Conclusion on classification
No existing harmonised classification in CLP Regulation Annex VI.
Environmental classification and labelling of a substance is based on data from short-term aquatic toxicity results (and long-term aquatic toxcity results if available), the ready biodegradability of the substance and an experimentally determined BCF (or if absent the measured octanol/water partition coefficient).
Data available :
- lowest L(E)C50 value comprised between 10 and 100 mg/L.
- no data on long-term aquatic toxicity.
- not rapidly biodegradable
- no experimental BCF data
- log Kow = 3.0 (20 °C)
Based on the above data, the substance is classified as Aquatic chronic 3 according to the CLP Regulation 1272/2008/EC & adaptation
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