Registration Dossier
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EC number: 481-150-8 | CAS number: 500011-86-9
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 25.11.2019 - 26.3.2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- 2009
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 2006
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: Knudsen cell
- Key result
- Test no.:
- #1
- Temp.:
- ca. 20 °C
- Vapour pressure:
- ca. 0 Pa
- Key result
- Test no.:
- #2
- Temp.:
- ca. 25 °C
- Vapour pressure:
- ca. 0 Pa
- Conclusions:
- 3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylic acid is a solid at 20°C with a vapour pressure of 5.6851 x 10-8 Pa.
- Executive summary:
By dynamic effusion method with a micro-balance vapour pressure for 3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylic acid was evaluated according to OECD guideline 104 (2006) and EC A.4 (2009).
The vapour pressure (P) of 3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylic acid is 5.6851 x 10-8 Pa at 20 °C and calculated at 1.3131 x 10-7 Pa at 25 °C.
The volatility (H) of 3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylic acid calculated at 20 °C is 1.8542 x 10 -9 Pa.m3.mol-1.
Reference
The mass of sample weighed for each assay was reported in the table below. The sample was placed in a Knudsen effusion cell. Then the cell was placed in the apparatus.
Assay No. |
Test temperature t (°C) |
Mass of test item (mg) |
Knudsen effusion cell aperture size (µm) |
Log P (Pa) |
1 |
150 |
13.08 |
279.9 |
-0.561 |
2 |
140 |
13.08 |
279.9 |
-0.950 |
3 |
130 |
13.08 |
279.9 |
-1.362 |
4 |
110 |
13.08 |
279.9 |
-2.168 |
| 5 | 100 | 13.08 | 279.9 | -2.574 |
No degradation of the test item was observed.
Description of key information
The vapour pressure (P) of 3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylic acid is 5.6851 x 10-8 Pa at 20 °C and calculated at 1.3131 x 10-7 Pa at 25 °C.
The volatility (H) of 3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylic acid calculated at 20 °C is 1.8542 x 10 -9 Pa.m3.mol-1.
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
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