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EC number: 271-766-3 | CAS number: 68607-67-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 72 hours
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Guideline study to GLP, reported 2018
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Test Substance: Reaction products of C11-C14 tert-alkylamine and formaldehyde
Activity: >98% active
Batch / Lot: HMK/370/12/1
CAS # & Composition: >98% reaction products of C11-C14 tert-alkylamine and formaldehyde (CAS# 68607-67-0)
Stability: Stable
Quoted Solubility: Insoluble in water
Observed Appearance: Clear, very pale, straw-like colored liquid - Analytical monitoring:
- yes
- Details on sampling:
- The concentrations of the test substance were verified by chemical analysis at time 0 and 72 hours
- Vehicle:
- no
- Details on test solutions:
- Based on the results of the preliminary range-find test the following nominal test, concentrations were assigned to the definitive test: 0.1, 0.2, 0.4, 0.8, 1.6, and 3.2 mg/L.
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
- Details on test organisms:
- Pseudokirchneriella subcapitata (formerly known as Selenastrum capricornutum UTEX #LB1648) culture used in this study was obtained from a stock maintained in freshwater algal assay medium
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 72 h
- Hardness:
- Prepared using OECD Recommended Freshwater Algal Culture Medium
- Test temperature:
- 20 C
- pH:
- Initial pH 8.1, reduced to as low as 7.41 during the course of the study
- Nominal and measured concentrations:
- Definitive test: nominal 0.1, 0.2, 0.4, 0.8, 1.6, and 3.2 mg/L.
Definitive test: measured 0.09, 0.17, 0.36, 0.68, 1.6, and 2.8 mg/L. - Details on test conditions:
- Environmental chamber (set at 20 C), was used and continuously illuminated by 6000 - 10,000 lux of light provided by overhead fluorescent lights.
Flasks, 250 mL in size, were randomly placed on the power unit and rotated continuously at ca 100 oscillations per minute - Reference substance (positive control):
- not required
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 1.46 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.43 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Validity criteria fulfilled:
- yes
Reference
Description of key information
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 1.46 mg/L
Additional information
Based on yield of the end of the Formaldehyde, reaction products with ethylenediamine, the results obtained were: NOEC = 1.0 mg/L and EC50 = 5.3 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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