Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-725-7 | CAS number: 87-13-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 25 July 2017 - 27 November 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7200 (Melting Point / Melting Range)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- Diethyl ethoxymethylenemalonate
- EC Number:
- 201-725-7
- EC Name:
- Diethyl ethoxymethylenemalonate
- Cas Number:
- 87-13-8
- Molecular formula:
- C10H16O5
- IUPAC Name:
- diethyl ethoxymethylenemalonate
- Test material form:
- liquid
Constituent 1
- Specific details on test material used for the study:
- - Batch n°: JC170405
- Analytical purity: 99.5%
- Expiration date: 12 April 2018
- Storage condition: at room temperature
Results and discussion
Melting / freezing point
- Key result
- Melting / freezing pt.:
- < -80 °C
- Atm. press.:
- 1 011 hPa
- Decomposition:
- no
Any other information on results incl. tables
Preliminary test
From the TGA curve it could be derived that the weight of the sample decreased significantly at 225°C. At 273°C the sample weight has decreased by 25%. After the experiment, no test item was observed in the sample container.
Main study
- Experiment 1: During cooling no effects were observed. During heating an endothermic peak between 200°C and 300°C was observed. The extrapolated onset temperature of the peak was 283.279°C. The effect was most likely obtained due to evaporation of the test item. After the experiment it was observed that the test item was evaporated from the sample container.
- Experiment 2 was performed to determine the duplicate melting temperature of the test item. Similar results as with Experiment 1 were obtained. The extrapolated onset of the evaporation peak was 270.150°C. After the experiment it was observed that the test item was evaporated from the sample container.
- Experiment 3 was performed to determine the duplicate melting temperature of the test item. Similar results as with Experiment 1 were obtained. The extrapolated onset of the boiling peak was 282.657°C. After the experiment it was observed that the test item was evaporated from the sample container.
- Support that boiling caused the endothermic peak, a higher heating rate of 50°C/minute was applied in Experiment 4. The extrapolated onset temperature of the evaporation peak was 285.290°C. The similar value obtained demonstrated that boiling of the test item was the reason for the endothermic effect. After the experiment it was observed that the test item was evaporated from the sample container.
- To further investigate the melting temperature of the test item, two subsamples of the test item were stored for 24 hours at -19.3 ± 0.4°C and at -79.9 ± 1.3°C respectively. It was observed after storage that the test item was a liquid (-20°C freezer) and a viscous liquid (-80°C freezer). According to this it was concluded that the melting temperature of the test item is < -80°C (< 193K).
Applicant's summary and conclusion
- Conclusions:
- The melting temperature of JNJ-39005525-AAA (EMME) was determined at < -80°C (< 193K) by applying a storage experiment in the freezer.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.