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EC number: 213-322-3 | CAS number: 937-14-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- GLP compliance:
- yes
- Type of method:
- HPLC estimation method
- Media:
- soil
- Test temperature:
- Column temperature < 39°C > 41°C
Autosampler temperature 4°C - Details on study design: HPLC method:
- EQUIPMENT
- Apparatus: Acquity UPLC system
- Type, material and dimension of analytical (guard) column: Acquity UPLC HSS Cyano, 100 mm x 2.1 mm i.d., dp = 1.8 µm
- Detection system: Acquity UPLC TUV detector
MOBILE PHASES
Mobile phase pH 2 55/45 (v/v) methanol/ buffer pH 2
Mobile phase pH 7 55/45 (v/v) methanol/ buffer pH 7 - Details on sampling:
- Additional QC samples were prepared and stored in the freezer (≤ -15°C) for at least 16 hours. On the day of analysis, the samples were thawed at room temperature and treated identically as freshly analyzed QC samples. The stored samples were found to be stable if the mean accuracy was in the range 70-110%.
- Computational methods:
- The equation of the regression line was: log k’ = 0.312 ´ log Koc – 0.913 (r = 0.98, n = 16).
- Key result
- Sample No.:
- #1
- Type:
- log Koc
- Remarks:
- Peak 1
- Value:
- 1.93 dimensionless
- pH:
- 2
- Temp.:
- 40 °C
- Key result
- Sample No.:
- #1
- Type:
- log Koc
- Remarks:
- Peak 1
- Value:
- < 1.26 dimensionless
- pH:
- 7
- Temp.:
- 40 °C
- Key result
- Sample No.:
- #1
- Type:
- log Koc
- Remarks:
- Peak 2
- Value:
- 1.93
- pH:
- 2
- Temp.:
- 40 °C
- Conclusions:
- The HPLC method using soil-adsorption-reference data was applied for the determination of the adsorption coefficient (Koc) of 3-Chloroperoxybenzoic Acid. The log Koc values of the test item peak 1 at pH 2 and pH 7 were: 1.93 and < 1.26. The log Koc values of the test item peak 2 at pH 7 was: 2.66.
- Executive summary:
The HPLC method using soil-adsorption-reference data was applied for the determination of the adsorption coefficient (Koc) of 3-Chloroperoxybenzoic Acid. The log Kocvalues of the test item peak 1 at pH 2 and pH 7 were: 1.93 and < 1.26. The log Koc values of the test item peak 2 at pH 7 was: 2.66.
Reference
pH 2: Kocof the Test Item |
|||||
Substance |
Retention time (min) |
log Koc |
Koc |
||
tr,1 |
tr,2 |
mean |
|||
Formamide (t0) |
0.738 |
0.743 |
0.741 |
|
|
Acetanilide |
0.922 |
0.932 |
|
1.26 |
|
Monuron |
1.103 |
1.112 |
|
1.99 |
|
2,5-Dichloroaniline |
1.229 |
1.234 |
|
2.55 |
|
Naphthalene |
1.412 |
1.416 |
|
2.75 |
|
Benzoic acid phenylester |
1.63 |
1.631 |
|
2.87 |
|
Fenthion |
2.114 |
2.107 |
|
3.31 |
|
Phenanthrene |
2.314 |
2.306 |
|
4.09 |
|
4,4’-DDT |
5.22 |
5.198 |
|
5.63 |
|
Test item |
1.099 |
1.106 |
1.103 |
1.93 |
8.5 ´ 101 |
pH 7: Kocof the Test Item |
|||||
Substance |
Retention time (min) |
log Koc |
Koc |
||
tr,1 |
tr,2 |
mean |
|||
Formamide (t0) |
0.762 |
0.755 |
0.759 |
|
|
Acetanilide |
0.973 |
0.965 |
|
1.26 |
|
Monuron |
1.172 |
1.164 |
|
1.99 |
|
2,5-Dichloroaniline |
1.29 |
1.298 |
|
2.55 |
|
Naphthalene |
1.497 |
1.503 |
|
2.75 |
|
Benzoic acid phenylester |
1.778 |
1.768 |
|
2.87 |
|
Fenthion |
2.249 |
2.263 |
|
3.31 |
|
Phenanthrene |
2.523 |
2.52 |
|
4.09 |
|
4,4’-DDT |
5.617 |
5.672 |
|
5.63 |
|
Test item – peak 1 |
0.561 |
0.561 |
0.561 |
< 1.26 |
< 1.8 ´ 101 |
Test item – peak 2 |
1.439 |
1.439 |
1.439 |
2.66 |
4.5 ´ 102 |
Description of key information
The HPLC method using soil-adsorption-reference data was applied for the determination of the adsorption coefficient (Koc) of 3-Chloroperoxybenzoic Acid. The log Koc values of the test item peak 1 at pH 2 and pH 7 were: 1.93 and < 1.26. The log Koc values of the test item peak 2 at pH 7 was: 2.66.
Key value for chemical safety assessment
- Koc at 20 °C:
- 457.1
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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