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EC number: - | CAS number: -
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Justification for type of information:
- Calculation of biodegradation in water is performed with EPI SUITE, BIOWIN v4.10, accepted estimation method from ECHA Guidelines.
- Principles of method if other than guideline:
- BIOWIN v4.10; part of: Estimation Programs Interface (EPI) Suite TM
- Key result
- Parameter:
- probability of ready biodegradability (QSAR/QSPR)
- Remarks:
- Linear Model
- Value:
- 0.807
- Remarks on result:
- readily biodegradable based on QSAR/QSPR prediction
- Key result
- Parameter:
- probability of ready biodegradability (QSAR/QSPR)
- Remarks:
- Non-Linear Model
- Value:
- 0.865
- Remarks on result:
- readily biodegradable based on QSAR/QSPR prediction
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Calculation of biodegradation in water with EPI SUITE, BIOWIN v4.10 : ready biodegradable
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Justification for type of information:
- Since the test item is a reaction mass of hexadecanoic anhydride and hexadecanoic acid, hexadecanoic acid was used for the read-across.
Calculation of biodegradation in water is performed with EPI SUITE, BIOWIN v4.10, accepted estimation method from ECHA Guidelines. - Reason / purpose for cross-reference:
- read-across source
- Principles of method if other than guideline:
- BIOWIN v4.10; part of: Estimation Programs Interface (EPI) Suite TM
- Key result
- Parameter:
- probability of ready biodegradability (QSAR/QSPR)
- Remarks:
- Linear Model
- Value:
- 0.807
- Remarks on result:
- readily biodegradable based on QSAR/QSPR prediction
- Key result
- Parameter:
- probability of ready biodegradability (QSAR/QSPR)
- Remarks:
- Non-Linear Model
- Value:
- 0.865
- Remarks on result:
- readily biodegradable based on QSAR/QSPR prediction
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Calculation of biodegradation in water with EPI SUITE, BIOWIN v4.10 : ready biodegradable
Referenceopen allclose all
Description of key information
Since hexadecanoic anhydride decomposes in hexadecanoic acid in water environment, only hexadecanoic acid was considered for the biodegradation in water of the test item. Hexadecanoic acid reults readily biodegradable using calculation method EPI SUITE, BIOWIN v4.10, therefore the test item is also considered readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
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