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EC number: 215-325-5 | CAS number: 1321-74-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data is from authorative database
- Qualifier:
- according to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- The short term aquatic toxicity of test material 1,2-di(ethenyl)benzene was evaluted for aquatic invertebrate
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- -IUPAC name: 1,2-di(ethenyl)benzene-Mol. formula: C10H10-Molecular Weight: 131.1969 g/mol- Substance type: Organic- Physical state: Pale, straw-colored liquid
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Daphnia magna
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 1.9 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The effect concentration (EC50) of test material 1,2-di(ethenyl)benzene on Daphnia magna after 48 h was observed to be 1.9 mg/l
- Executive summary:
Short term toxicity to aquatic invertebrate was evaluated for Daphnia magna for the test chemical 1,2-di(ethenyl)benzene for 48 h . The effect concentration (EC50) of test material 1,2-di(ethenyl)benzene on Daphnia magna after 48 h was observed to be 1.9 mg/l. On the basis of above effect concentration it was considered that the test chemical is toxic to aquatic invertebrate . Hence, it can be classified as aquatic chronic-2 as per CLP criteria
Reference
Description of key information
Short term toxicity to aquatic invertebrate:
Short term toxicity to aquatic invertebrate was evaluated for Daphnia magna for the test chemical 1,2-di(ethenyl)benzene for 48 h . The effect concentration (EC50) of test material 1,2-di(ethenyl)benzene on Daphnia magna after 48 h was observed to be 1.9 mg/l. On the basis of above effect concentration it was considered that the test chemical is toxic to aquatic invertebrate . Hence, it can be classified as aquatic chronic-2 as per CLP criteria
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1.9 mg/L
Additional information
Short term toxicity to aquatic invertebrate:
Data for target chemical 1,2-di(ethenyl)benzene along with its structurally similar read across substance was used to summarize the short term toxicity of test chemical:
1.Short term toxicity to aquatic invertebrate was evaluated for Daphnia magna for the test chemical 1,2-di(ethenyl)benzene for 48 h . The effect concentration (EC50) of test material 1,2-di(ethenyl)benzene on Daphnia magna after 48 h was observed to be 1.9 mg/l. On the basis of above effect concentration it was considered that the test chemical is toxic to aquatic invertebrate . Hence, it can be classified as aquatic chronic-2 as per CLP criteria.
2.Short term toxicity of test material was evaluated for aqutaic invertebrate Daphnia magna according to OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test). The effect concentration (EC50) of test chemical on Daphnia magna was evaluted to be 2.6 mg/l aftter 48 h of test exposure.
On the basis of above effect concentration it can be concluded that the test material is toxic to aquatic invertebrate . Hence, the test material an be classified as aquatic chronic - 2
3.Short term toxicity to aquatic invertebrate was evaluated for the test material , Daphnia magna Straus neonates, less than 20 hours old was used for the test . A 100 mg/ml stock solution of the test material in reagent grade DMF was prepared by weight to a precision of 0.1 mg; additional stocks were prepared by serial dilution.The test concentration selected were 0.56, 1 .00, 1.80, 3.20, and 5.60 mg/l.
The concentration of test material lethal to 50% of the test population and 95% confidence limits were determined for the 24 and 48 hour exposure periods by the Spearman-Karber Estimator.
The 48-hour LC50 and 95% confidence limits in Daphnia magna were 3.34 (2.69-4.13) mg/L. The 48-hour NOEC was observed to be 0.56 mg/L.
On the basis of above effect concentration it can be concluded that the test material is toxic to aquatic invertebrate . Hence, the test material an be classified as aquatic chronic - 2
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