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EC number: 306-227-4 | CAS number: 96690-34-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to the analogue justification attached to IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across: supporting information
- Duration:
- 72 h
- Dose descriptor:
- EC10
- Effect conc.:
- 4.9 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC90
- Effect conc.:
- > 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 3.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- LOEC
- Effect conc.:
- 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC10
- Effect conc.:
- 3.5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: yield
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 7.1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: yield
- Duration:
- 72 h
- Dose descriptor:
- EC90
- Effect conc.:
- > 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: yield
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 3.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: yield
- Duration:
- 72 h
- Dose descriptor:
- LOEC
- Effect conc.:
- 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: yield
- Conclusions:
- The EC50 for growth rate was determined to be >10.0 mg/L and the NOEC was determined to be at 3.2 mg/L.
- Executive summary:
In a 72 hour acute toxicity study (CAS 80939 -62 -4, RCC, 2007), the cultures of the green algal species Pseudokirchneriella subcapitata were exposed to the test item under static conditions in accordance with OECD guideline 201. Due to its low solubility in water the test item was tested by preparing Water-Accommodated-Fractions (WAFs). The loading rates of 0, 0.032, 0.1, 0.32,1.0,3.2, 10 mg/L was tested. The NOEC and EC50 values based on the loading rates on growth rate were 3.2 and >10 mg/L, respectively. The NOEC and EC50 values based on loading rates on Yield were 3.2 and 7.1 mg/L, respectively.
Reference
Description of key information
ErC50 (72h) >10.0 mg/L (Pseudokirchneriella subcapitata, OECD 201, nominal, read-across to CAS 80939 -62 -4)
ErC10 (72h) = 4.9 mg/L (Pseudokirchneriella subcapitata, OECD 201, nominal, read-across to CAS 80939 -62 -4)
NOEC (72h) = 3.2 mg/L (Pseudokirchneriella subcapitata, OECD 201, nominal, read-across to CAS 80939 -62 -4)
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 3.2 mg/L
Additional information
No data are available on the toxicity of Amines, C12-14-tert-alkyl, mixed sec-Bu and iso-Bu phosphates (CAS No. 96690-34-5) to aquatic algae. Therefore data from the analogue substance Amines, C11-14-branched alkyl, monohexyl and dihexyl phosphates (CAS 80939-62-4) were used as read across. This read-across is in accordance with Regulation (EC) No. 1907/2006 Annex XI, 1.5 and justified in detail in the overall summary (IUCLID Chapter 6.1) and within the analogue justification attached in IUCLID Section 13.
In a 72 hour acute toxicity study (CAS 80939 -62 -4, RCC, 2007), the cultures of the green algal species Pseudokirchneriella subcapitata were exposed to the test item under static conditions in accordance with OECD guideline 201 and GLP. Due to its low solubility in water the test item was tested by preparing Water-Accommodated-Fractions (WAFs). Nominal loading rates of 0.032, 0.1, 0.32,1.0, 3.2, 10 mg/L and a blank were tested. The NOEC and EC50 values based on the nominal loading rates on growth rate were 3.2 and >10 mg/L, respectively. The NOEC and EC50 values based on loading rates on Yield were 3.2 and 7.1 mg/L, respectively.
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