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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information

Data source

Reference
Reference Type:
publication
Title:
Dibenzylamine - a novel blocker of the voltage-dependent K+ current in myocardial mouse cells
Author:
Doepner B, Koopmann R, Knopp A, Hirche HJ, Benndorf K
Year:
2001
Bibliographic source:
Naunyn-scghmiedeberg's arch Pharmacol 364,9-13

Materials and methods

Type of study / information:
in vitro investigation
Principles of method if other than guideline:
in vitro treatment of myocardial cells of mice with DBA
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Dibenzylamine
EC Number:
203-117-7
EC Name:
Dibenzylamine
Cas Number:
103-49-1
Molecular formula:
C14H15N
IUPAC Name:
dibenzylamine
Details on test material:
no further data

Results and discussion

Any other information on results incl. tables

The study show that dibenzylamine is a blocker of the voltage-dependent K-ion current in the mouse ventricular heart cells

Applicant's summary and conclusion