Registration Dossier
Registration Dossier
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EC number: 227-133-9 | CAS number: 5675-51-4
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2020-02 to 2020-04
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Radiolabelling:
- no
- Analytical monitoring:
- yes
- Duration:
- 5 d
- pH:
- 4
- Temp.:
- 25 °C
- Initial conc. measured:
- 206.3 µg/L
- Duration:
- 5 d
- pH:
- 7
- Temp.:
- 25 °C
- Initial conc. measured:
- 196.4 µg/L
- Duration:
- 5 d
- pH:
- 9
- Temp.:
- 25 °C
- Initial conc. measured:
- 224 µg/L
- Preliminary study:
- A preliminary study was carried out which showed the test substance to be stable at all tested pH-values. The recovery rates of the substance after 5 days of testing showed values of 118% (pH 4), 114 % (pH 7) and 111 % (pH 9).
- Transformation products:
- no
- % Recovery:
- 118
- pH:
- 4
- Temp.:
- 25 °C
- Duration:
- 5 d
- Remarks on result:
- hydrolytically stable based on preliminary test
- % Recovery:
- 114
- pH:
- 7
- Temp.:
- 25 °C
- Duration:
- 5 d
- Remarks on result:
- hydrolytically stable based on preliminary test
- % Recovery:
- 111
- pH:
- 9
- Temp.:
- 25 °C
- Duration:
- 5 d
- Remarks on result:
- hydrolytically stable based on preliminary test
- Remarks on result:
- hydrolytically stable based on preliminary test
- Validity criteria fulfilled:
- yes
Reference
Description of key information
The substance is hydrolytically stable at all tested pH values.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
