Registration Dossier
Registration Dossier
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EC number: 212-550-0 | CAS number: 825-90-1
Endpoint summary
Administrative data
Description of key information
Short-term toxicity tests are available for fish, invertebrates, algae and micro organisms with LC50/EC50 values greater than 28.6 mg/L.
Additional information
Aquatic toxicity potential of substance sodium 4-hydroxybenzenesulfonate was evaluated in studies conducted with fish, invertebrates, algae and bacteria. The OECD Toolbox v 4.4.1 predicted the 96 h LC50 to fish as 28.6 mg/L using Leadscope model. In a publication that has been referenced in US EPA ECOTOX - AQUIRE database 96 h (100 h) LC50 for Lepomis macrochirus (Bluegill) is 19616 mg/L.
A study was performed to assess the acute toxicity of the test item to Daphnia magna. The method followed was designed to be compatible with the OECD Guidelines for Testing of Chemicals (April 2004) No 202, "Daphnia sp., Acute Immobilisation Test" referenced as Method C.2 of Commission Regulation (EC) No. 440/2008. 48 h exposure of Daphnia magna to the test item gave EC50 values of greater than 100 mg/L. The No Observed Effect Concentration was 100 mg/L.
A study was performed to assess the effect of the test item on the growth of the green alga Pseudokirchneriella subcapitata following OECD Guidelines for Testing of Chemicals (2006) No 201, "Freshwater Alga and Cyanobacteria, Growth Inhibition Test" referenced as Method C.3 of Commission Regulation (EC) No 761/2009. Exposure of Pseudokirchneriella subcapitata to the test item gave EC50 values of greater than 100 mg/L. The No Observed Effect Concentration was 100 mg/L.
A study was performed to assess the effect of the test item on the respiration of activated sewage sludge. The method followed was designed to be compatible with the OECD Guidelines for Testing of Chemicals (2010) No. 209 "Activated Sludge, Respiration Inhibition Test (Carbon and Ammonium Oxidation)". The effect of the test item on the respiration of activated sewage sludge gave a 3 h EC50 value of greater than 1000 mg/L. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 1000 mg/L.
Hence, based on the above results, sodium 4-hydroxybenzenesulfonate can be considered as not toxic to the aquatic ecosystem.
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