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Diss Factsheets
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EC number: 259-627-5 | CAS number: 55406-53-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Endpoint summary
Administrative data
Description of key information
Based on the experimental data available the test item is considered to be acutely toxic to both, marine and freshwater fish.
Available data on short-term and long-term toxicity to aquatic invertebrates imply toxic properties of the substance.
Additional information
Short-term toxicity to fish
Sheapshed minnow was exposed to the test item with nominal concentrations of 1.5, 0.90, 0.54, 0.32 and 0.19 mg/L under flow through conditions up to 96 h. Based on results obtained in this study, the test item is considered to be acutely toxic to fish.
Rainbow trout was exposed to test item nominal concenctrations of 150, 90, 54, 32 and 19 µg/L for 96 h under flow through conditions. Under the test conditions, the test item is considered to be acutely toxic to fish.
Bluegill sunfish was exposed to the test item with nominal concentrations of 500, 300, 180, 110 and 65 µg/L for 96 h under flow through conditions. Under the test conditions, the test item is considered to be acutely toxic to fish.
Short-term toxicity to aquatic invertebrates
In an 48 h acute toxicity study with daphnids under static conditions an LC50 value of 0.645 mg/L was determined.
Long-term toxicity to fish
In a GLP and guideline compliant study, early life stages of fathead minnow were exposed to test item concentrations of 57; 27; 19; 8.4; 4 µg/L (measured). Body length and wet weight were found to be the most sensitive indications of the test item toxicity. Respective NOEC was determined to be 8.4 µg/L.
Long-term toxicity to aquatic invertebrates
Chronic toxicity to water flea, daphnia magna, was studied under flow through conditions applying concentrations of 12.5, 25, 50, 100, 200 and 400 µg/L for 21 d. NOEC was determined to be 0.0499 mg/L
Toxicity to aquatic algae
The test item had a statistically significant inhibition effect on the growth (biomass and growth rate) of Scenedesmus subspicatus after the exposure period of 72 hours at concentrations of 10 µg/L (= 72-hour LOEC) and above. EC50 value for growth rate was determiend to be 53 µg/L.
Toxicity to microorganisms
In an OECD 209 equivalent study an EC50 of 44 mg/L was determined. The EC10 was determined to be 6.0 mg/L.
In a supporting study the inhibitory effect of the test item on the respiration rate of aerobic wastewater microorganisms of activated sludge was investigated in a 3-hour respiration inhibition test. NOEC was determined to be 45 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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