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EC number: 611-799-6 | CAS number: 59121-99-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 999
- Report date:
- 1999
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- 1,4,6,10-Dodecatetraen-3-ol,3,7,11-trimethyl-,(4E,6E)-
- EC Number:
- 611-799-6
- Cas Number:
- 59121-99-2
- Molecular formula:
- C15H24O
- IUPAC Name:
- 1,4,6,10-Dodecatetraen-3-ol,3,7,11-trimethyl-,(4E,6E)-
- Test material form:
- liquid: viscous
- Details on test material:
- - Name of test material (as cited in study report): Vinylpseudoionol
- Molecular formula (if other than submission substance): C15H24O
- Molecular weight (if other than submission substance): 220.36 g/mol
- Physical state: viscous-liquid
- Analytical purity: 87.1 %
- Impurities (identity and concentrations): 1.2 % water
- Purity test date: not indicated
- Lot/batch No.: Technikumscharge M401
- Limited storage: no
- Stability under test conditions:
- Storage condition of test material: ca. 4 °C, under nitrogen
- Water solubility: poorly water soluble
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- The concentration control analyses were performed with test solutions of the following nominal
concentrations (mg/I) of the test substance : 0, 10, 100 mg/L
At the start of the test (after 0 h) samples from vessels without daphnids, at the end of the test (after 48 h) samples from vessels with and without daphnids were analyzed.
Test solutions
- Details on test solutions:
- Reagents: deionized water (Milli Q-system); acetonitrile (Riedel-de-Haen) ; potassium dihydrogenphosphate (Merck); phosphoric acid 85%(Riedel-de-Haen); reference standard and carrier were delivered by the sponsor.
Sample preparation: For calibration the reference standard was dissolved in acetonitrile ; the stock solutions were diluted with 0.01 M KH2PO4 pH3/acetonitrile (1 /1 v/v) .
Measuring parameters:
Column: Purosper RP-18 5 µm 125 * 3 mm i.d. (Merck)
Mobile phase: 0.01 M KH2PO4 pH3/acetonitrile (38/62 v/v)
Flow rate: 1.0 ml/min
Injection volume: 20 µl
Temperature: ambient
Detection: UV at 290 nm
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: water flea
- Strain:
- Source : The clone of Dahpnia magna STRAUS 1820 used was supplied by the Instutut National de Recherche Chimique Appliquee, France in 1978. Fron this data on this clone was cultured and bred continously in the Laboratory of Ecology of BASF AG in Ludwigshafen
- Age at study initiation (mean and range, SD): 2 - 24 h- Weight at study initiation (mean and range, SD):
- Feeding during test: none
ACCLIMATION
- Acclimation conditions (same as test or not): yes
- Type and amount of food: green algae
- Feeding frequency: daily
- Health during acclimation (any mortality observed): no
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 2.20 - 3.20 mmol/L
- Test temperature:
- 20.3 - 20.7 °C
- pH:
- 7.9 - 8.2
- Dissolved oxygen:
- 7.7 - 8.8 mg/L
- Nominal and measured concentrations:
- Nominal: 0, 0, 078, 0.156, 0.313, 0.625, 1.25, 2.5, 5, 10 mg/L
analysed nominal concentrations (measured at 0 and 48 h) : 0 (< 0.05), 10 (0.07 - 0.16/0.19), 100 (0.71 - 2.07) mg/L - Details on test conditions:
- TEST SYSTEM
- Test vessel: flat bottom glass tubes, nominal 20 ml
- Type (delete if not applicable): open
- Material, size, headspace, fill volume: 10 ml fill volume
- Aeration: no
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
- Biomass loading rate: 0.5 animals/ ml
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: M4 medium
OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: 16:8 h day night regime
- Light intensity: About 2 - 7 µE/(m2~s) at a wave length of 400 - 700 nm
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : mobility after 0, 3, 6, 24 and 48 h
TEST CONCENTRATIONS
- Spacing factor for test concentrations: 2 - Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.026 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Reported statistics and error estimates:
- For the statistical calculation of the EC50 the probit method (Finney) was used .
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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