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EC number: 413-060-1 | CAS number: 19186-97-1
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
FR-370: A REPRODUCTION STUDY WITH THE EARTHWORM IN AN ARTIFICIAL SOIL SUBSTRATE
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil macroorganisms:
- 1 000 mg/kg soil dw
- Long-term EC10, LC10 or NOEC for soil macroorganisms:
- 62.5 mg/kg soil dw
Additional information
In a 14 -d Acute toxicity study with FR-370 to earthworms the LC50 was determined to be > 1000 mg/kg soil dry weight.
In a reproductive toxicity study to the earthworm Eisienia fetida, there was no mortality of adult earthworms exposed to FR-370 at 62.5, 125, 250, 500 and 1000 mg/kg dry soil for 28 days and no statistically significant effects upon adult earthworm weight. One treatment group, the 125 mg/kg treatment group, had a greater than 50% reduction in reproduction relative to the control group however the EC50 value for reproduction calculated using non linear regression analysis was greater than 1000 mg/kg dry soil.
There were statistically significant (p=0.05) effects on the numbers of juveniles produced in the 125, 250, 500 and 1000 kg/mg treatment groups. Therefore, the LOEC was determined to be 125 mg/kg and the NOEC 62.5 mg/kg dry soil.
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