Registration Dossier
Registration Dossier
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EC number: 259-423-6 | CAS number: 54982-83-1
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of the substance to fish was determined in a study conducted according to OECD TG 203 and GLP. In this flow-through test, groups of 10 rainbow trout (Oncorhynchus mykiss) were exposed for 96 hours to nominal test concentrations of 0.10, 0.18, 0.32, 0.56 and 1.0 mg/L. Samples of the test solutions were taken at 0, 48 and 96 hours and analysed by gas chromatography (GC) using a flame ionisation detector. Measured concentrations were 0.10, 0.20, 0.33, 0.62 and 1.1 mg/L, respectively. As the mean measured concentrations were 100-111% of the nominal exposure concentrations, nominal concentrations were used for calculation and for reporting of results. There were no mortalities in the dilution water or solvent control vessels. After 96 hours, mortality was observed only at the highest concentration tested. Throughout the test, fish exhibited the following symptoms of toxicity: loss of balance, dark discoloration, irregular respiration, laboured respiration, sounding, rapid respiration and hyperactivity. Cumulative mortality was 70% after the 96-hour exposure period. Based on these findings the 96-h LC50 was determined at 0.88 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.88 mg/L
Additional information
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