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EC number: 269-119-5 | CAS number: 68187-67-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Between 20 March 2000 and 19 July 2000
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 000
- Report date:
- 2000
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.1 (Acute Toxicity for Fish)
- Deviations:
- yes
- Remarks:
- Some test fish were of larger size than recommended in the test guideline for zebra fish. This deviation is not considered relevant to the result.
- GLP compliance:
- yes
Test material
- Reference substance name:
- Amines, C12-14-alkyl, isooctyl phosphates
- EC Number:
- 269-119-5
- EC Name:
- Amines, C12-14-alkyl, isooctyl phosphates
- Cas Number:
- 68187-67-7
- Molecular formula:
- C19H42NPO4 - C29H63NPO4
- IUPAC Name:
- Amines, C12-14-tert-alkyl, isooctyl mono phosphates
- Test material form:
- liquid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- Daily analysis of test concnetrations 4mg/l and 8 mg/l and the control by TOC determination
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- TEST ORGANISM
- Common name: Zebra Fish
- Source: Bio International B.V (Netherlands)
- Age at study initiation): 17 - 18 weeks
- Length at study initiation : 2.5 - 3.5 cm
Study design
- Test type:
- static
- Water media type:
- freshwater
- Remarks:
- Synthetic freshwater in accordance with ISO
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- 13.9dH
- Test temperature:
- 21 - 22°C
- pH:
- 7.6 - 8.1
- Dissolved oxygen:
- 7.9 - 8.8 mg/l
- Nominal and measured concentrations:
- Nominal cocentrations 0.5, 1, 2, 4 and 8 mg/l
- Details on test conditions:
- Static test with test vessels 300 x 135 x 200mm and 5l test medium. photoperiod of 16 hours light / 8 hours dark.
Results and discussion
Effect concentrationsopen allclose all
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LL0
- Effect conc.:
- ca. 1 mg/L
- Nominal / measured:
- nominal
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LL100
- Effect conc.:
- ca. 2 mg/L
- Nominal / measured:
- nominal
- Basis for effect:
- mortality (fish)
- Details on results:
- Please see attached backgroung material for mortality data and results of test concentrations.
Visible effects on appearance and behaviour of fish
At 2mg/l - After 2 hours 10 animals showed sluggish swimming action. After 24 hours 3 animlaa showed sluggish and abnormal swimming action and 6 animals showed sluggish swimming action. After 48 hours 3 animals showed sluggish and abnormal swimming action.
At 4 mg/l - After 2 hours 10 animals showed sluggish swimming action
At 8 mg/l - 4 animals were motionless and showed uncontrolled swimming action when touched.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The acute toxicity of the test item was determined in a 96-hour static test. The 96hour LL0 was estimated to be 1mg/l and the 96hour LL100 was estimated to be 2mg/l.
- Executive summary:
The acute toxicity of the test item was determined in a 96-hour static test. Due to the heterogenous composition of the test item, for the purposes of the test, the test medium was prepared as a Water Accommodated Fraction (WAF). The results were based on nominal loading rates.
96 hour LL0 was estimated to be 1mg/l
96 hour LL100 was estimated to be 2mg/l.
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