Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
see T.E.S.T. (US EPA) v4.1

Data source

Reference
Title:
No information
Author:
Anonymous
Year:
2016
Bibliographic source:
Toxicity Estimation Software Tool (T.E.S.T.) v4.1, US EPA

Materials and methods

Test guideline
Guideline:
other: QSAR
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2-dimethyl-1,3-dioxane-4,6-dione
EC Number:
217-992-8
EC Name:
2,2-dimethyl-1,3-dioxane-4,6-dione
Cas Number:
2033-24-1
Molecular formula:
C6H8O4
IUPAC Name:
2,2-dimethyl-1,3-dioxane-4,6-dione
Test material form:
solid: particulate/powder

Test animals

Species:
rat
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Key result
Sex:
male/female
Dose descriptor:
LD50
Effect level:
ca. 4 000 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met